Diagnosis of celiac disease on a gluten-free diet: a multicenter prospective quasi-experimental clinical study

Diagnosis of celiac disease on a gluten-free diet: a multicenter prospective quasi-experimental clinical study

Abstract Background Diagnosing celiac disease (CD) in individuals adhering to a gluten-free diet (GFD) presents significant challenges. Current guidelines recommend a gluten challenge (GC) lasting at least 6–8 weeks, which has several limitations. Our aim was to compare four approaches previously pr...

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Main Authors: Sara Gómez-Aguililla, Sergio Farrais, Natalia López-Palacios, Beatriz Arau, Carla Senosiain, María Corzo, Nora Fernandez-Jimenez, Ángela Ruiz-Carnicer, Fernando Fernández-Bañares, Bárbara P. González-García, Eva Tristán, Ana Montero-Calle, María Garranzo-Asensio, Isabel Casado, Mar Pujals, Juana María Hernández, Jorge Infante-Menéndez, Garbiñe Roy, Carolina Sousa, Concepción Núñez
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Medicine
Subjects:
Celiac disease
Gluten challenge
Gluten-free diet
CD8+ T cells
Online Access:https://doi.org/10.1186/s12916-025-04008-y
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