Prevalent chromosome fusion in Vibrio cholerae O1

Prevalent chromosome fusion in Vibrio cholerae O1

Abstract Two circular chromosomes are a defining feature of the bacterial family Vibrionaceae, including the pathogen Vibrio cholerae, with rare reports of isolates with a single, fused chromosome. Here, we use long-read sequencing to analyse 467 V. cholerae O1 isolates from 47 cholera patients and...

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Main Authors: Aline Cuénod, Denise Chac, Ashraful I. Khan, Fahima Chowdhury, Randy W. Hyppa, Susan M. Markiewicz, Amelia Rice, Akhil Kholwadwala, Stephen B. Calderwood, Edward T. Ryan, Jason B. Harris, Regina C. LaRocque, Taufiqur R. Bhuiyan, Gerald R. Smith, Firdausi Qadri, Patrick Lypaczewski, Ana A. Weil, B. Jesse Shapiro
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60699-0
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