Molecular surveillance of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Mozambique, 2023

Molecular surveillance of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Mozambique, 2023

Abstract Background Rapid diagnostic tests (RDTs) based on the detection of Plasmodium falciparum histidine rich protein 2 (PfHRP2) are widely used for the diagnostic of P. falciparum in Africa. However, deletions of the pfhrp2 and pfhrp3 genes can lead to false negative test results and compromise...

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Main Authors: Clemente da Silva, Dário Tembisse, Pau Cisteró, Eduard Rovira-Vallbona, Neide Canana, Paulino da Costa, Gloria Matambisso, Andrés Aranda-Díaz, Henriques Mbeve, Nelo Ndimande, Alcido Timana, Aura Hunguana, Simone Boene, Arnau Pujol, Bernardete Rafael, Bryan Greenhouse, Sónia Enosse, Francisco Saúte, Baltazar Candrinho, Alfredo Mayor
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Malaria Journal
Subjects:
Molecular surveillance
Diagnostics
RDT
Malaria
pfhrp2/3 gene deletions
Mozambique
Online Access:https://doi.org/10.1186/s12936-024-05230-4
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