Patrolling monocytes mediate virus neutralizing IgG effector functions: beyond neutralization capacity

Patrolling monocytes mediate virus neutralizing IgG effector functions: beyond neutralization capacity

Neutralizing antibodies (nAbs) are pivotal in developing fast, broadly protective therapeutics against novel pandemic viruses. Despite their well-known direct neutralization capacity, their effector mechanisms via Fc receptors remain poorly understood. Identifying the types of effector cells engaged...

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Bibliographic Details
Main Authors: Abdelrahman Elwy, Swati Dhiman, Hossam Abdelrahman, Julia Specht, Theresa Charlotte Christ, Julia Falkenstein, Harpreet Kaur, Lisa Holnsteiner, Judith Lang, Matthias Mack, Falk Nimmerjahn, Wiebke Hansen, Karl Sebastian Lang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
IgG
neutralizing antibodies
patrolling monocytes
LCMV
passive immunization
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1600056/full
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