Sinus Augmentation by Platelet-Rich Fibrin Alone: A Report of Two Cases with Histological Examinations

In sinus floor augmentation of an atrophic posterior maxilla, platelet-rich fibrin (PRF) has been used as a graft material. We herein report two cases with histological evaluations of PRF after the surgery. The first case was a 28-year-old female with an atrophic right posterior maxilla who was trea...

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Main Authors: Naofumi Aoki, Takeo Kanayama, Michinori Maeda, Koichiro Horii, Hironori Miyamoto, Keinoshin Wada, Yasutaka Ojima, Tsukasa Tsuchimochi, Yasuyuki Shibuya
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2016/2654645
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author Naofumi Aoki
Takeo Kanayama
Michinori Maeda
Koichiro Horii
Hironori Miyamoto
Keinoshin Wada
Yasutaka Ojima
Tsukasa Tsuchimochi
Yasuyuki Shibuya
author_facet Naofumi Aoki
Takeo Kanayama
Michinori Maeda
Koichiro Horii
Hironori Miyamoto
Keinoshin Wada
Yasutaka Ojima
Tsukasa Tsuchimochi
Yasuyuki Shibuya
author_sort Naofumi Aoki
collection DOAJ
description In sinus floor augmentation of an atrophic posterior maxilla, platelet-rich fibrin (PRF) has been used as a graft material. We herein report two cases with histological evaluations of PRF after the surgery. The first case was a 28-year-old female with an atrophic right posterior maxilla who was treated with sinus floor augmentation and simultaneous implant placement using PRF as the sole graft material in our hospital. Twenty-four months after surgery, the implant was unfortunately removed because of occlusal overloading by parafunctional habits. During implant replacement, a tissue sample was obtained from the site of augmentation with PRF and was evaluated histologically. The second case was a 58-year-old man with severe alveolar atrophy of the right maxilla who underwent lateral sinus augmentation using only PRF in a two-stage procedure in our hospital. Samples were obtained at the second-stage surgery and histological examinations were performed. As a result, new bone formation was confirmed histologically in both cases. Our findings show that the use of PRF as a graft material during sinus floor augmentation induces natural bone regeneration.
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spelling doaj-art-241e0a34f94f417e8001132ff53e845d2025-02-03T01:25:44ZengWileyCase Reports in Dentistry2090-64472090-64552016-01-01201610.1155/2016/26546452654645Sinus Augmentation by Platelet-Rich Fibrin Alone: A Report of Two Cases with Histological ExaminationsNaofumi Aoki0Takeo Kanayama1Michinori Maeda2Koichiro Horii3Hironori Miyamoto4Keinoshin Wada5Yasutaka Ojima6Tsukasa Tsuchimochi7Yasuyuki Shibuya8Department of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, JapanHakata Dental Clinic, Fukuoka 812-0011, JapanDepartment of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, JapanDepartment of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, JapanDepartment of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, JapanDepartment of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, JapanDepartment of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, JapanDepartment of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, JapanDepartment of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, JapanIn sinus floor augmentation of an atrophic posterior maxilla, platelet-rich fibrin (PRF) has been used as a graft material. We herein report two cases with histological evaluations of PRF after the surgery. The first case was a 28-year-old female with an atrophic right posterior maxilla who was treated with sinus floor augmentation and simultaneous implant placement using PRF as the sole graft material in our hospital. Twenty-four months after surgery, the implant was unfortunately removed because of occlusal overloading by parafunctional habits. During implant replacement, a tissue sample was obtained from the site of augmentation with PRF and was evaluated histologically. The second case was a 58-year-old man with severe alveolar atrophy of the right maxilla who underwent lateral sinus augmentation using only PRF in a two-stage procedure in our hospital. Samples were obtained at the second-stage surgery and histological examinations were performed. As a result, new bone formation was confirmed histologically in both cases. Our findings show that the use of PRF as a graft material during sinus floor augmentation induces natural bone regeneration.http://dx.doi.org/10.1155/2016/2654645
spellingShingle Naofumi Aoki
Takeo Kanayama
Michinori Maeda
Koichiro Horii
Hironori Miyamoto
Keinoshin Wada
Yasutaka Ojima
Tsukasa Tsuchimochi
Yasuyuki Shibuya
Sinus Augmentation by Platelet-Rich Fibrin Alone: A Report of Two Cases with Histological Examinations
Case Reports in Dentistry
title Sinus Augmentation by Platelet-Rich Fibrin Alone: A Report of Two Cases with Histological Examinations
title_full Sinus Augmentation by Platelet-Rich Fibrin Alone: A Report of Two Cases with Histological Examinations
title_fullStr Sinus Augmentation by Platelet-Rich Fibrin Alone: A Report of Two Cases with Histological Examinations
title_full_unstemmed Sinus Augmentation by Platelet-Rich Fibrin Alone: A Report of Two Cases with Histological Examinations
title_short Sinus Augmentation by Platelet-Rich Fibrin Alone: A Report of Two Cases with Histological Examinations
title_sort sinus augmentation by platelet rich fibrin alone a report of two cases with histological examinations
url http://dx.doi.org/10.1155/2016/2654645
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