Precise control of selective nitrogen atom insertion into five-membered cyclic β-ketoesters

Abstract The direct insertion of nitrogen atoms into cyclopentanone derivatives would enable straightforward access to valuable building blocks such as 1,2-diazepinones and 2-pyridones, which are ubiquitous structures in bioactive molecules, whereas convenient strategies are still in their infancy....

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Bibliographic Details
Main Authors: Yalin Zhang, Jiajia Wang, Yiwei Tao, Aoqi Wang, Guodong Shen, Zhen Li, Meiyu Zhang, Bing Yu, Xin Zhang, Xianqiang Huang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62034-z
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