Human adenovirus type 7 (HAdV-7) infection induces pulmonary vascular endothelial injury through the activation of endothelial autophagy

Human adenovirus type 7 (HAdV-7) infection induces pulmonary vascular endothelial injury through the activation of endothelial autophagy

Abstract Background HAdV-7 is a prevalent pathogen that can cause severe pneumonia in children. Previous studies have shown a significant increase in serum levels of vascular permeability factor (VPF/VEGF) and viral load in pediatric patients with fatal HAdV-7 infection, suggesting potential damage...

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Bibliographic Details
Main Authors: Zhihe Chen, Zhongying Yang, Lifen Rao, Changgen Li, Na Zang, Enmei Liu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Respiratory Research
Subjects:
HAdV-7
Endothelial autophagy
Endothelium injury
Viremia
ALI/ARDS
Online Access:https://doi.org/10.1186/s12931-024-03025-4
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