Regulation of DNA repair mechanism in human glioma xenograft cells both in vitro and in vivo in nude mice.

<h4>Background</h4>Glioblastoma Multiforme (GBM) is the most lethal form of brain tumor. Efficient DNA repair and anti-apoptotic mechanisms are making glioma treatment difficult. Proteases such as MMP9, cathepsin B and urokinase plasminogen activator receptor (uPAR) are over expressed in...

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Bibliographic Details
Main Authors: Shivani Ponnala, Krishna Kumar Veeravalli, Chandramu Chetty, Dzung H Dinh, Jasti S Rao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0026191
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