Clostridium sordellii as a Cause of Fatal Septic Shock in a Child with Hemolytic Uremic Syndrome

Clostridium sordellii is a toxin producing ubiquitous gram-positive anaerobe, mainly associated with trauma, soft tissue skin infections, and gynecologic infection. We report a unique case of a new strain of Clostridium sordellii (not present in the Center for Disease Control (CDC) database) infecti...

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Main Authors: Rebekah Beyers, Michael Baldwin, Sevilay Dalabih, Abdallah Dalabih
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2014/237674
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author Rebekah Beyers
Michael Baldwin
Sevilay Dalabih
Abdallah Dalabih
author_facet Rebekah Beyers
Michael Baldwin
Sevilay Dalabih
Abdallah Dalabih
author_sort Rebekah Beyers
collection DOAJ
description Clostridium sordellii is a toxin producing ubiquitous gram-positive anaerobe, mainly associated with trauma, soft tissue skin infections, and gynecologic infection. We report a unique case of a new strain of Clostridium sordellii (not present in the Center for Disease Control (CDC) database) infection induced toxic shock syndrome in a previously healthy two-year-old male with colitis-related hemolytic uremic syndrome (HUS). The patient presented with dehydration, vomiting, and bloody diarrhea. He was transferred to the pediatric critical care unit (PICU) for initiation of peritoneal dialysis (PD). Due to increased edema and intolerance of PD, he was transitioned to hemodialysis through a femoral vascular catheter. He subsequently developed severe septic shock with persistent leukocytosis and hypotension, resulting in subsequent death. Stool culture confirmed Shiga toxin producing Escherichia coli 0157:H7. A blood culture was positively identified for Clostridium sordellii. Clostridium sordelli is rarely reported in children; to our knowledge this is the first case described in a pediatric patient with HUS.
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spelling doaj-art-23ebd052629b46f7b844aa977d48b7d22025-08-20T02:04:13ZengWileyCase Reports in Pediatrics2090-68032090-68112014-01-01201410.1155/2014/237674237674Clostridium sordellii as a Cause of Fatal Septic Shock in a Child with Hemolytic Uremic SyndromeRebekah Beyers0Michael Baldwin1Sevilay Dalabih2Abdallah Dalabih3Department of Child Health, University of Missouri, 400 Keene Street, Columbia, MO 65201, USADepartment of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO 65201, USADepartment of Child Health, University of Missouri, 400 Keene Street, Columbia, MO 65201, USADepartment of Child Health, University of Missouri, 400 Keene Street, Columbia, MO 65201, USAClostridium sordellii is a toxin producing ubiquitous gram-positive anaerobe, mainly associated with trauma, soft tissue skin infections, and gynecologic infection. We report a unique case of a new strain of Clostridium sordellii (not present in the Center for Disease Control (CDC) database) infection induced toxic shock syndrome in a previously healthy two-year-old male with colitis-related hemolytic uremic syndrome (HUS). The patient presented with dehydration, vomiting, and bloody diarrhea. He was transferred to the pediatric critical care unit (PICU) for initiation of peritoneal dialysis (PD). Due to increased edema and intolerance of PD, he was transitioned to hemodialysis through a femoral vascular catheter. He subsequently developed severe septic shock with persistent leukocytosis and hypotension, resulting in subsequent death. Stool culture confirmed Shiga toxin producing Escherichia coli 0157:H7. A blood culture was positively identified for Clostridium sordellii. Clostridium sordelli is rarely reported in children; to our knowledge this is the first case described in a pediatric patient with HUS.http://dx.doi.org/10.1155/2014/237674
spellingShingle Rebekah Beyers
Michael Baldwin
Sevilay Dalabih
Abdallah Dalabih
Clostridium sordellii as a Cause of Fatal Septic Shock in a Child with Hemolytic Uremic Syndrome
Case Reports in Pediatrics
title Clostridium sordellii as a Cause of Fatal Septic Shock in a Child with Hemolytic Uremic Syndrome
title_full Clostridium sordellii as a Cause of Fatal Septic Shock in a Child with Hemolytic Uremic Syndrome
title_fullStr Clostridium sordellii as a Cause of Fatal Septic Shock in a Child with Hemolytic Uremic Syndrome
title_full_unstemmed Clostridium sordellii as a Cause of Fatal Septic Shock in a Child with Hemolytic Uremic Syndrome
title_short Clostridium sordellii as a Cause of Fatal Septic Shock in a Child with Hemolytic Uremic Syndrome
title_sort clostridium sordellii as a cause of fatal septic shock in a child with hemolytic uremic syndrome
url http://dx.doi.org/10.1155/2014/237674
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AT sevilaydalabih clostridiumsordelliiasacauseoffatalsepticshockinachildwithhemolyticuremicsyndrome
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