A review of combined imaging and therapeutic applications based on MNMs
Magnetic nanomaterials (MNMs) are nanoscale materials with inherent magnetic properties that can respond to external magnetic fields, typically composed of magnetic metals or metal oxides. These materials exhibit broad application prospects in medical imaging, targeted drug delivery, and cancer ther...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Chemistry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2025.1595376/full |
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| author | Yiqing Yang Peihong Teng Shaonan Yu Yuran Meng Jinjie Zuo He Guo Guifeng Liu |
| author_facet | Yiqing Yang Peihong Teng Shaonan Yu Yuran Meng Jinjie Zuo He Guo Guifeng Liu |
| author_sort | Yiqing Yang |
| collection | DOAJ |
| description | Magnetic nanomaterials (MNMs) are nanoscale materials with inherent magnetic properties that can respond to external magnetic fields, typically composed of magnetic metals or metal oxides. These materials exhibit broad application prospects in medical imaging, targeted drug delivery, and cancer therapy due to their exceptional magnetic properties, biocompatibility, and surface functionalization capabilities. As multifunctional imaging contrast agents, magnetic nanomaterials have been extensively employed in magnetic resonance imaging, computed tomography, and positron emission tomography to enhance multimodal imaging, thereby improving image resolution and diagnostic accuracy. Additionally, as targeted drug carriers, they can be guided by external magnetic fields to achieve precise drug delivery, enhancing therapeutic efficacy while minimizing systemic side effects. In therapeutic applications, magnetic nanomaterials have been utilized in magnetic hyperthermia therapy and photothermal therapy, where they generate localized heat via alternating magnetic fields or photothermal conversion effects, enabling tumor microenvironment modulation and precise tumor ablation. This review systematically summarizes recent advances in the use of MNMs for medical imaging and therapy, with a particular focus on key technical challenges and emerging opportunities to achieve synergistic imaging and therapeutic functions. This work aims to provide valuable insight into the development of MNMs for applications in precision medicine and personalized therapy. |
| format | Article |
| id | doaj-art-23e12065340e41bb9de9834ebd1d11dc |
| institution | Kabale University |
| issn | 2296-2646 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj-art-23e12065340e41bb9de9834ebd1d11dc2025-08-20T03:48:23ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462025-05-011310.3389/fchem.2025.15953761595376A review of combined imaging and therapeutic applications based on MNMsYiqing Yang0Peihong Teng1Shaonan Yu2Yuran Meng3Jinjie Zuo4He Guo5Guifeng Liu6Department of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaMagnetic nanomaterials (MNMs) are nanoscale materials with inherent magnetic properties that can respond to external magnetic fields, typically composed of magnetic metals or metal oxides. These materials exhibit broad application prospects in medical imaging, targeted drug delivery, and cancer therapy due to their exceptional magnetic properties, biocompatibility, and surface functionalization capabilities. As multifunctional imaging contrast agents, magnetic nanomaterials have been extensively employed in magnetic resonance imaging, computed tomography, and positron emission tomography to enhance multimodal imaging, thereby improving image resolution and diagnostic accuracy. Additionally, as targeted drug carriers, they can be guided by external magnetic fields to achieve precise drug delivery, enhancing therapeutic efficacy while minimizing systemic side effects. In therapeutic applications, magnetic nanomaterials have been utilized in magnetic hyperthermia therapy and photothermal therapy, where they generate localized heat via alternating magnetic fields or photothermal conversion effects, enabling tumor microenvironment modulation and precise tumor ablation. This review systematically summarizes recent advances in the use of MNMs for medical imaging and therapy, with a particular focus on key technical challenges and emerging opportunities to achieve synergistic imaging and therapeutic functions. This work aims to provide valuable insight into the development of MNMs for applications in precision medicine and personalized therapy.https://www.frontiersin.org/articles/10.3389/fchem.2025.1595376/fullmagnetic nanomaterialsmultimodal imagingcancer therapytheranosticspersonalized therapy |
| spellingShingle | Yiqing Yang Peihong Teng Shaonan Yu Yuran Meng Jinjie Zuo He Guo Guifeng Liu A review of combined imaging and therapeutic applications based on MNMs Frontiers in Chemistry magnetic nanomaterials multimodal imaging cancer therapy theranostics personalized therapy |
| title | A review of combined imaging and therapeutic applications based on MNMs |
| title_full | A review of combined imaging and therapeutic applications based on MNMs |
| title_fullStr | A review of combined imaging and therapeutic applications based on MNMs |
| title_full_unstemmed | A review of combined imaging and therapeutic applications based on MNMs |
| title_short | A review of combined imaging and therapeutic applications based on MNMs |
| title_sort | review of combined imaging and therapeutic applications based on mnms |
| topic | magnetic nanomaterials multimodal imaging cancer therapy theranostics personalized therapy |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2025.1595376/full |
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