Correlation of mean platelet volume and red blood cell distribution width with obstructive sleep apnoea syndrome severity
Introduction: Mean platelet volume (MPV) and red blood cll distribution width (RDW) have been assosiated with sleep apnea syndrome severity. Objective: To investigate the correlation of mean platelet volume and red blood cell distribution width with obesity sleep apnoea syndrome (OSAS) severity. Met...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-05-01
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| Series: | Lung India |
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| Online Access: | https://journals.lww.com/10.4103/lungindia.lungindia_422_24 |
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| author | Kyriaki Cholidou Nektarios Anagnostopoulos Konstantinos Bartziokas Konstantinos Vafeiadis Agamemnon Bakakos Aggelos Vontetsianos Vasiliki Gogou Zoi Sotiropoulou Christina Anagnostopoulou Anna Papasarantou Paschalis Steiropoulos Petros Bakakos Andriana I. Papaioannou |
| author_facet | Kyriaki Cholidou Nektarios Anagnostopoulos Konstantinos Bartziokas Konstantinos Vafeiadis Agamemnon Bakakos Aggelos Vontetsianos Vasiliki Gogou Zoi Sotiropoulou Christina Anagnostopoulou Anna Papasarantou Paschalis Steiropoulos Petros Bakakos Andriana I. Papaioannou |
| author_sort | Kyriaki Cholidou |
| collection | DOAJ |
| description | Introduction:
Mean platelet volume (MPV) and red blood cll distribution width (RDW) have been assosiated with sleep apnea syndrome severity.
Objective:
To investigate the correlation of mean platelet volume and red blood cell distribution width with obesity sleep apnoea syndrome (OSAS) severity.
Methods:
Ninety patients underwent PSG. Patients with an apnoea-hypopnoea index (AHI) <5 were used as controls. Patients with AHI >5 were divided into mild: 5 ≤ AHI <15, moderate: 15≤ AHI <30 and severe OSAS: AHI ≥30. Patients >65 years, with body mass index (BMI) >40, central sleep apnoea syndrome, cardiovascular or other significant comorbidities were excluded. Blood sample collection occurred one day before polysomnography (PSG).
Results:
Sixty-four patients were included in our study. Fifty-seven (89.1%) had OSAS (16% mild, 25% moderate and 48.4% severe) while the remaining 7 (10.1%) were used as controls. MPV was similar among groups [8.1 (7.1, 9.2) vs 7.9 (6.8, 10.1) vs 8.5 (7.4, 9.1) vs 8.4 (7.6, 9.7), P = .930 for control, mild, moderate and severe OSAS, respectively]. RDW did not differ between OSAS patients and control [median (IQR) 14.4 (13.4, 15.3) vs 14.0 (13.5, 16.7), P = .950], while there was no significant difference among different stages of OSAS severity [14.0 (13.5, 16.7) vs 13.9 (11.4, 14.8) vs 14.4 (14.0, 15.3) vs 14.4 (13.3, 15.6), P = .517] for control, mild, moderate and severe OSAS, respectively.
Conclusion:
OSAS patients have elevated levels of RDW and MPV compared to controls; however, there was no association between OSAS severity and MPV or RDW. |
| format | Article |
| id | doaj-art-23e079bb0ddb433987beebf4be6f5e4a |
| institution | DOAJ |
| issn | 0970-2113 0974-598X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Lung India |
| spelling | doaj-art-23e079bb0ddb433987beebf4be6f5e4a2025-08-20T02:56:15ZengWolters Kluwer Medknow PublicationsLung India0970-21130974-598X2025-05-0142317918510.4103/lungindia.lungindia_422_24Correlation of mean platelet volume and red blood cell distribution width with obstructive sleep apnoea syndrome severityKyriaki CholidouNektarios AnagnostopoulosKonstantinos BartziokasKonstantinos VafeiadisAgamemnon BakakosAggelos VontetsianosVasiliki GogouZoi SotiropoulouChristina AnagnostopoulouAnna PapasarantouPaschalis SteiropoulosPetros BakakosAndriana I. PapaioannouIntroduction: Mean platelet volume (MPV) and red blood cll distribution width (RDW) have been assosiated with sleep apnea syndrome severity. Objective: To investigate the correlation of mean platelet volume and red blood cell distribution width with obesity sleep apnoea syndrome (OSAS) severity. Methods: Ninety patients underwent PSG. Patients with an apnoea-hypopnoea index (AHI) <5 were used as controls. Patients with AHI >5 were divided into mild: 5 ≤ AHI <15, moderate: 15≤ AHI <30 and severe OSAS: AHI ≥30. Patients >65 years, with body mass index (BMI) >40, central sleep apnoea syndrome, cardiovascular or other significant comorbidities were excluded. Blood sample collection occurred one day before polysomnography (PSG). Results: Sixty-four patients were included in our study. Fifty-seven (89.1%) had OSAS (16% mild, 25% moderate and 48.4% severe) while the remaining 7 (10.1%) were used as controls. MPV was similar among groups [8.1 (7.1, 9.2) vs 7.9 (6.8, 10.1) vs 8.5 (7.4, 9.1) vs 8.4 (7.6, 9.7), P = .930 for control, mild, moderate and severe OSAS, respectively]. RDW did not differ between OSAS patients and control [median (IQR) 14.4 (13.4, 15.3) vs 14.0 (13.5, 16.7), P = .950], while there was no significant difference among different stages of OSAS severity [14.0 (13.5, 16.7) vs 13.9 (11.4, 14.8) vs 14.4 (14.0, 15.3) vs 14.4 (13.3, 15.6), P = .517] for control, mild, moderate and severe OSAS, respectively. Conclusion: OSAS patients have elevated levels of RDW and MPV compared to controls; however, there was no association between OSAS severity and MPV or RDW.https://journals.lww.com/10.4103/lungindia.lungindia_422_24biomarkersmean platelet volumeobstructive sleep apnoea syndromered blood cell distribution widthseverity |
| spellingShingle | Kyriaki Cholidou Nektarios Anagnostopoulos Konstantinos Bartziokas Konstantinos Vafeiadis Agamemnon Bakakos Aggelos Vontetsianos Vasiliki Gogou Zoi Sotiropoulou Christina Anagnostopoulou Anna Papasarantou Paschalis Steiropoulos Petros Bakakos Andriana I. Papaioannou Correlation of mean platelet volume and red blood cell distribution width with obstructive sleep apnoea syndrome severity Lung India biomarkers mean platelet volume obstructive sleep apnoea syndrome red blood cell distribution width severity |
| title | Correlation of mean platelet volume and red blood cell distribution width with obstructive sleep apnoea syndrome severity |
| title_full | Correlation of mean platelet volume and red blood cell distribution width with obstructive sleep apnoea syndrome severity |
| title_fullStr | Correlation of mean platelet volume and red blood cell distribution width with obstructive sleep apnoea syndrome severity |
| title_full_unstemmed | Correlation of mean platelet volume and red blood cell distribution width with obstructive sleep apnoea syndrome severity |
| title_short | Correlation of mean platelet volume and red blood cell distribution width with obstructive sleep apnoea syndrome severity |
| title_sort | correlation of mean platelet volume and red blood cell distribution width with obstructive sleep apnoea syndrome severity |
| topic | biomarkers mean platelet volume obstructive sleep apnoea syndrome red blood cell distribution width severity |
| url | https://journals.lww.com/10.4103/lungindia.lungindia_422_24 |
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