Study on the impact of COVID-19 epidemic and agent disease risk simulation model based on individual factors in Xi’an City

IntroductionSince the first discovery and reporting of the COVID - 19 pandemic towards the end of 2019, the virus has rapidly propagated across the world. This has led to a remarkable spike in the number of infections. Even now, doubt lingers over whether it has completely disappeared. Moreover, the...

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Main Authors: Wen Dong, Henan Yao, Wei-Na Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1547601/full
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author Wen Dong
Wen Dong
Henan Yao
Henan Yao
Wei-Na Wang
author_facet Wen Dong
Wen Dong
Henan Yao
Henan Yao
Wei-Na Wang
author_sort Wen Dong
collection DOAJ
description IntroductionSince the first discovery and reporting of the COVID - 19 pandemic towards the end of 2019, the virus has rapidly propagated across the world. This has led to a remarkable spike in the number of infections. Even now, doubt lingers over whether it has completely disappeared. Moreover, the issue of restoring normal life while ensuring safety continues to be a crucial challenge that public health agencies and people globally are eager to tackle.MethodsTo thoroughly understand the epidemic’s outbreak and transmission traits and formulate timely prevention measures to fully safeguard human lives and property, this paper presents an agent - based model incorporating individual - level factors.ResultsThe model designates Xi'an—where a characteristic disease outbreak occurred—as the research area. The simulation results demonstrate substantial consistency with official records, effectively validating the model’s applicability, adaptability, and generalizability. This validated capacity enables accurate prediction of epidemic trends and comprehensive assessment of disease risks.DiscussionFrom late 2021 to early 2022, it employs a one - to - one population simulation approach and simulates epidemic impacts and disease risks. Initially, using building statistical data in the study area, the model reconstructs the local real - world geographical environment. Leveraging data from the seventh national population census, it also replicates the study area’s population characteristics. Next, the model takes into account population mobility, contact tracing, patient treatment, and the diagnostic burden of COVID - 19 - like influenza symptoms. It integrates epidemic transmission impact parameters into the model framework. Eventually, the model’s results are compared with official data for validation, and it’s applied to hypothetical scenarios. It provides scientific theoretical tools to support the implementation of government - driven prevention and control measures. Additionally, it facilitates the adjustment of individual behavioral guidelines, promoting more effective epidemic management.
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spelling doaj-art-23dae4b48118422f9b747754487de0722025-08-20T03:52:47ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882025-05-011510.3389/fcimb.2025.15476011547601Study on the impact of COVID-19 epidemic and agent disease risk simulation model based on individual factors in Xi’an CityWen Dong0Wen Dong1Henan Yao2Henan Yao3Wei-Na Wang4Faculty of Geography, Yunnan Normal University, Kunming, ChinaGeographic Information System (GIS) Technology Engineering Research Centre for West-China Resources and Environment of Educational Ministry, Yunnan Normal University, Kunming, ChinaFaculty of Geography, Yunnan Normal University, Kunming, ChinaGeographic Information System (GIS) Technology Engineering Research Centre for West-China Resources and Environment of Educational Ministry, Yunnan Normal University, Kunming, ChinaNetwork and Information Center, Yunnan Normal University, Kunming, ChinaIntroductionSince the first discovery and reporting of the COVID - 19 pandemic towards the end of 2019, the virus has rapidly propagated across the world. This has led to a remarkable spike in the number of infections. Even now, doubt lingers over whether it has completely disappeared. Moreover, the issue of restoring normal life while ensuring safety continues to be a crucial challenge that public health agencies and people globally are eager to tackle.MethodsTo thoroughly understand the epidemic’s outbreak and transmission traits and formulate timely prevention measures to fully safeguard human lives and property, this paper presents an agent - based model incorporating individual - level factors.ResultsThe model designates Xi'an—where a characteristic disease outbreak occurred—as the research area. The simulation results demonstrate substantial consistency with official records, effectively validating the model’s applicability, adaptability, and generalizability. This validated capacity enables accurate prediction of epidemic trends and comprehensive assessment of disease risks.DiscussionFrom late 2021 to early 2022, it employs a one - to - one population simulation approach and simulates epidemic impacts and disease risks. Initially, using building statistical data in the study area, the model reconstructs the local real - world geographical environment. Leveraging data from the seventh national population census, it also replicates the study area’s population characteristics. Next, the model takes into account population mobility, contact tracing, patient treatment, and the diagnostic burden of COVID - 19 - like influenza symptoms. It integrates epidemic transmission impact parameters into the model framework. Eventually, the model’s results are compared with official data for validation, and it’s applied to hypothetical scenarios. It provides scientific theoretical tools to support the implementation of government - driven prevention and control measures. Additionally, it facilitates the adjustment of individual behavioral guidelines, promoting more effective epidemic management.https://www.frontiersin.org/articles/10.3389/fcimb.2025.1547601/fullCOVID-19individual factoragent modelgovernment macro intervention policysimulation and prediction
spellingShingle Wen Dong
Wen Dong
Henan Yao
Henan Yao
Wei-Na Wang
Study on the impact of COVID-19 epidemic and agent disease risk simulation model based on individual factors in Xi’an City
Frontiers in Cellular and Infection Microbiology
COVID-19
individual factor
agent model
government macro intervention policy
simulation and prediction
title Study on the impact of COVID-19 epidemic and agent disease risk simulation model based on individual factors in Xi’an City
title_full Study on the impact of COVID-19 epidemic and agent disease risk simulation model based on individual factors in Xi’an City
title_fullStr Study on the impact of COVID-19 epidemic and agent disease risk simulation model based on individual factors in Xi’an City
title_full_unstemmed Study on the impact of COVID-19 epidemic and agent disease risk simulation model based on individual factors in Xi’an City
title_short Study on the impact of COVID-19 epidemic and agent disease risk simulation model based on individual factors in Xi’an City
title_sort study on the impact of covid 19 epidemic and agent disease risk simulation model based on individual factors in xi an city
topic COVID-19
individual factor
agent model
government macro intervention policy
simulation and prediction
url https://www.frontiersin.org/articles/10.3389/fcimb.2025.1547601/full
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