TNF stimulation primarily modulates transcriptional burst size of NF‐κB‐regulated genes
Abstract Cell‐to‐cell heterogeneity is a feature of the tumor necrosis factor (TNF)‐stimulated inflammatory response mediated by the transcription factor NF‐κB, motivating an exploration of the underlying sources of this noise. Here, we combined single‐transcript measurements with computational mode...
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| Main Authors: | Victor L Bass, Victor C Wong, M Elise Bullock, Suzanne Gaudet, Kathryn Miller‐Jensen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2021-07-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/msb.202010127 |
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