Synthesis and properties of carbon quantum dots as an antimicrobial agent and detection of ciprofloxacin
Abstract This work reports a novel one-pot hydrothermal synthesis of N-CQDs using Solanum nigrum L. as sustainable carbon source and triethylamine as nitrogen provider. The resulting N-CQDs were systematically characterized with TEM, SEM, FT-IR, XPS, XRD, and UV–Visible. Significantly, the N-CQDs ex...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-14383-4 |
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| Summary: | Abstract This work reports a novel one-pot hydrothermal synthesis of N-CQDs using Solanum nigrum L. as sustainable carbon source and triethylamine as nitrogen provider. The resulting N-CQDs were systematically characterized with TEM, SEM, FT-IR, XPS, XRD, and UV–Visible. Significantly, the N-CQDs exhibited substantial antimicrobial efficacy against both S. aureus and E. coli bacterial strains, with minimum inhibitory concentration values of 1.2 mg/mL and 1.1 mg/mL, respectively. Moreover, the N-CQDs demonstrated pronounced fluorescence enhancement upon interaction with ciprofloxacin, displaying exceptional selectivity and sensitivity, with a calculated LOD of 316 nM. The feasibility of employing N-CQDs as fluorescent probes for ciprofloxacin detection was systematically validated through practical application in honey analysis. This study introduces a novel approach for the fabrication of N-CQDs derived from natural botanical sources, underscoring their potential dual functionality as fluorescent sensors and antimicrobial materials. |
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| ISSN: | 2045-2322 |