The Alteration of Brain Function by the Improvement of Periodontal Tissues and Occlusal State

Objective. In this study, we have introduced a case in which the effective blood oxygenation level-dependent signal on functional magnetic resonance imaging (fMRI) was altered by the improvement of periodontal tissue and occlusal function in a patient with periodontitis Stage II Grade B. Material an...

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Main Authors: Kosuke Muraoka, Masafumi Oda, Kenichi Yoshino, Tatsurou Tanaka, Masaki Morishita, Taiji Nakamura, Ryota Kibune, Jyunpei Tokunaga, Kazuo Sonoki, Yasuhiro Morimoto, Keisuke Nakashima, Shuji Awano
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2022/5383893
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author Kosuke Muraoka
Masafumi Oda
Kenichi Yoshino
Tatsurou Tanaka
Masaki Morishita
Taiji Nakamura
Ryota Kibune
Jyunpei Tokunaga
Kazuo Sonoki
Yasuhiro Morimoto
Keisuke Nakashima
Shuji Awano
author_facet Kosuke Muraoka
Masafumi Oda
Kenichi Yoshino
Tatsurou Tanaka
Masaki Morishita
Taiji Nakamura
Ryota Kibune
Jyunpei Tokunaga
Kazuo Sonoki
Yasuhiro Morimoto
Keisuke Nakashima
Shuji Awano
author_sort Kosuke Muraoka
collection DOAJ
description Objective. In this study, we have introduced a case in which the effective blood oxygenation level-dependent signal on functional magnetic resonance imaging (fMRI) was altered by the improvement of periodontal tissue and occlusal function in a patient with periodontitis Stage II Grade B. Material and Methods. A 61-year-old female patient requiring periodontal treatment was diagnosed as having periodontitis Stage II Grade B via clinical and radiographic examinations. Her past medical history included type 2 diabetes, hypertension, and hyperlipidemia. Following the patient’s informed written consent, the periodontal initial treatment provided to the patient included tooth brushing instruction and scaling and root planing; however, occlusal adjustment was not performed at this stage. Occlusal force and fMRI results were also evaluated at the initial and reevaluation examinations. Results. After the periodontal initial treatment had been performed, it was noted that the patient’s periodontal tissue and occlusal force had improved. It was also evident from fMRI that cerebral blood flow had been activated in the insula, primary motor cortex, and premotor cortex. Conclusion. This result suggested that the periodontal ligament had recovered and the periodontal ligament neuron had been further subjected to clenching in the insula so that the muscle spindle sensation impacted the motor cortex.
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spelling doaj-art-23d5703cbfb544a7a3af808705f2073e2025-08-20T03:54:57ZengWileyCase Reports in Dentistry2090-64552022-01-01202210.1155/2022/5383893The Alteration of Brain Function by the Improvement of Periodontal Tissues and Occlusal StateKosuke Muraoka0Masafumi Oda1Kenichi Yoshino2Tatsurou Tanaka3Masaki Morishita4Taiji Nakamura5Ryota Kibune6Jyunpei Tokunaga7Kazuo Sonoki8Yasuhiro Morimoto9Keisuke Nakashima10Shuji Awano11Science of Oral Functions DepartmentDivision of Oral and Maxillofacial RadiologySection of Primary Dental EducationGraduate School of Medical and Dental SciencesScience of Oral Functions DepartmentScience of Oral Functions DepartmentScience of Oral Functions DepartmentScience of Oral Functions DepartmentUnit of Interdisciplinary EducationDivision of Oral and Maxillofacial RadiologyScience of Oral Functions DepartmentScience of Oral Functions DepartmentObjective. In this study, we have introduced a case in which the effective blood oxygenation level-dependent signal on functional magnetic resonance imaging (fMRI) was altered by the improvement of periodontal tissue and occlusal function in a patient with periodontitis Stage II Grade B. Material and Methods. A 61-year-old female patient requiring periodontal treatment was diagnosed as having periodontitis Stage II Grade B via clinical and radiographic examinations. Her past medical history included type 2 diabetes, hypertension, and hyperlipidemia. Following the patient’s informed written consent, the periodontal initial treatment provided to the patient included tooth brushing instruction and scaling and root planing; however, occlusal adjustment was not performed at this stage. Occlusal force and fMRI results were also evaluated at the initial and reevaluation examinations. Results. After the periodontal initial treatment had been performed, it was noted that the patient’s periodontal tissue and occlusal force had improved. It was also evident from fMRI that cerebral blood flow had been activated in the insula, primary motor cortex, and premotor cortex. Conclusion. This result suggested that the periodontal ligament had recovered and the periodontal ligament neuron had been further subjected to clenching in the insula so that the muscle spindle sensation impacted the motor cortex.http://dx.doi.org/10.1155/2022/5383893
spellingShingle Kosuke Muraoka
Masafumi Oda
Kenichi Yoshino
Tatsurou Tanaka
Masaki Morishita
Taiji Nakamura
Ryota Kibune
Jyunpei Tokunaga
Kazuo Sonoki
Yasuhiro Morimoto
Keisuke Nakashima
Shuji Awano
The Alteration of Brain Function by the Improvement of Periodontal Tissues and Occlusal State
Case Reports in Dentistry
title The Alteration of Brain Function by the Improvement of Periodontal Tissues and Occlusal State
title_full The Alteration of Brain Function by the Improvement of Periodontal Tissues and Occlusal State
title_fullStr The Alteration of Brain Function by the Improvement of Periodontal Tissues and Occlusal State
title_full_unstemmed The Alteration of Brain Function by the Improvement of Periodontal Tissues and Occlusal State
title_short The Alteration of Brain Function by the Improvement of Periodontal Tissues and Occlusal State
title_sort alteration of brain function by the improvement of periodontal tissues and occlusal state
url http://dx.doi.org/10.1155/2022/5383893
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