Giant Thoracolumbosacral Myelomeningocele: A Case Report

Neural tube defects are a broad spectrum of congenital developmental anomalies that include cranial defects and open and closed spinal dysraphism. Myelomeningocele is a common form of spinal dysraphism most commonly seen in the lumbosacral region. Giant myelomeningoceles are rare occurrences. We her...

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Main Authors: Abhijit Acharya, Souvagya Panigrahi, Rama Chandra Deo, Satya Bhusan Senapati, Ashok Kumar Mahapatra
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2025-08-01
Series:Indian Journal of Neurosurgery
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1780520
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author Abhijit Acharya
Souvagya Panigrahi
Rama Chandra Deo
Satya Bhusan Senapati
Ashok Kumar Mahapatra
author_facet Abhijit Acharya
Souvagya Panigrahi
Rama Chandra Deo
Satya Bhusan Senapati
Ashok Kumar Mahapatra
author_sort Abhijit Acharya
collection DOAJ
description Neural tube defects are a broad spectrum of congenital developmental anomalies that include cranial defects and open and closed spinal dysraphism. Myelomeningocele is a common form of spinal dysraphism most commonly seen in the lumbosacral region. Giant myelomeningoceles are rare occurrences. We hereby present the case of a 7-month-old infant with a history of large swelling over the thoracic lumbar region (circumference of 42 cm and diameter of 12.5 cm) that was progressively increasing in size with occasional cerebrospinal fluid (CSF) leakage from the swelling. There was associated progressive increasing size of the head size circumference (51 cm) as well for the past 6 months. There was no movement of both lower limbs since birth without any sensation up to the groin. On evaluation, the infant was found to have gross hydrocephalous. The Evans index was 0.4 with Chiari 2 malformation and a giant thoracolumbosacral myelomeningocele. The patient underwent a low-pressure ventriculoperitoneal (VP) shunt on the right side, followed by the repair of the giant myelomeningocele. The post-op period was uneventful with no CSF leakage or skin necrosis. The infant was discharged on day 5. Giant myelomeningoceles are quite a challenge for neurosurgeons due to the high risk of skin edge necrosis, CSF leaks, meningoencephalitis, etc. Here we managed our case with utmost intraoperative surgical skills and postoperative management due to which our patient was discharged in a satisfactory condition without any complication. This case is supposed to be largest myelomeningocele in the world literature to date.
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institution Kabale University
issn 2277-954X
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language English
publishDate 2025-08-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
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series Indian Journal of Neurosurgery
spelling doaj-art-23d174b68f8147e0aa7659b2836a40712025-08-20T03:40:21ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Neurosurgery2277-954X2277-91672025-08-01140219419810.1055/s-0044-1780520Giant Thoracolumbosacral Myelomeningocele: A Case ReportAbhijit Acharya0https://orcid.org/0000-0001-9793-8406Souvagya Panigrahi1Rama Chandra Deo2Satya Bhusan Senapati3Ashok Kumar Mahapatra4Department of Neurosurgery, IMS and SUM Hospital, SOA University Kalinga Nagar, Bhubaneswar, Odisha, IndiaDepartment of Neurosurgery, IMS and SUM Hospital, SOA University Kalinga Nagar, Bhubaneswar, Odisha, IndiaDepartment of Neurosurgery, IMS and SUM Hospital, SOA University Kalinga Nagar, Bhubaneswar, Odisha, IndiaDepartment of Neurosurgery, IMS and SUM Hospital, SOA University Kalinga Nagar, Bhubaneswar, Odisha, IndiaDepartment of Neurosurgery, IMS and SUM Hospital, SOA University Kalinga Nagar, Bhubaneswar, Odisha, IndiaNeural tube defects are a broad spectrum of congenital developmental anomalies that include cranial defects and open and closed spinal dysraphism. Myelomeningocele is a common form of spinal dysraphism most commonly seen in the lumbosacral region. Giant myelomeningoceles are rare occurrences. We hereby present the case of a 7-month-old infant with a history of large swelling over the thoracic lumbar region (circumference of 42 cm and diameter of 12.5 cm) that was progressively increasing in size with occasional cerebrospinal fluid (CSF) leakage from the swelling. There was associated progressive increasing size of the head size circumference (51 cm) as well for the past 6 months. There was no movement of both lower limbs since birth without any sensation up to the groin. On evaluation, the infant was found to have gross hydrocephalous. The Evans index was 0.4 with Chiari 2 malformation and a giant thoracolumbosacral myelomeningocele. The patient underwent a low-pressure ventriculoperitoneal (VP) shunt on the right side, followed by the repair of the giant myelomeningocele. The post-op period was uneventful with no CSF leakage or skin necrosis. The infant was discharged on day 5. Giant myelomeningoceles are quite a challenge for neurosurgeons due to the high risk of skin edge necrosis, CSF leaks, meningoencephalitis, etc. Here we managed our case with utmost intraoperative surgical skills and postoperative management due to which our patient was discharged in a satisfactory condition without any complication. This case is supposed to be largest myelomeningocele in the world literature to date.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1780520myelomeningoceleneurosurgeryspinal dysraphismtethered cord
spellingShingle Abhijit Acharya
Souvagya Panigrahi
Rama Chandra Deo
Satya Bhusan Senapati
Ashok Kumar Mahapatra
Giant Thoracolumbosacral Myelomeningocele: A Case Report
Indian Journal of Neurosurgery
myelomeningocele
neurosurgery
spinal dysraphism
tethered cord
title Giant Thoracolumbosacral Myelomeningocele: A Case Report
title_full Giant Thoracolumbosacral Myelomeningocele: A Case Report
title_fullStr Giant Thoracolumbosacral Myelomeningocele: A Case Report
title_full_unstemmed Giant Thoracolumbosacral Myelomeningocele: A Case Report
title_short Giant Thoracolumbosacral Myelomeningocele: A Case Report
title_sort giant thoracolumbosacral myelomeningocele a case report
topic myelomeningocele
neurosurgery
spinal dysraphism
tethered cord
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1780520
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AT souvagyapanigrahi giantthoracolumbosacralmyelomeningoceleacasereport
AT ramachandradeo giantthoracolumbosacralmyelomeningoceleacasereport
AT satyabhusansenapati giantthoracolumbosacralmyelomeningoceleacasereport
AT ashokkumarmahapatra giantthoracolumbosacralmyelomeningoceleacasereport