Endovascular thrombectomy for the treatment of acute ischemic stroke
ABSTRACT Few patients benefit from the current standard treatment for acute ischemic stroke (AIS), encouraging the development of new treatments. Objective To systematically review the literature on the efficacy and/or safety of endovascular thrombectomy in AIS compared to standard treatment and to...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações
2015-01-01
|
| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015005010102&lng=en&tlng=en |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850247791776890880 |
|---|---|
| author | Cleusa P. Ferri Anna Buehler Uri Adrian Prync Flato Paulo Puglia Junior Jefferson G. Fernandes |
| author_facet | Cleusa P. Ferri Anna Buehler Uri Adrian Prync Flato Paulo Puglia Junior Jefferson G. Fernandes |
| author_sort | Cleusa P. Ferri |
| collection | DOAJ |
| description | ABSTRACT Few patients benefit from the current standard treatment for acute ischemic stroke (AIS), encouraging the development of new treatments. Objective To systematically review the literature on the efficacy and/or safety of endovascular thrombectomy in AIS compared to standard treatment and to identify ongoing randomized controlled trials (RCTs). Method Searches for RCTs were performed in Medline/Embase, and for ongoing trials: International Clinical Trial Registry Platform, Clinicaltrials.gov and ISRCTN registry (to June 15th, 2015). Results From the eight published RCTs, five showed the superiority of treatment that includes thrombectomy compared to standard care alone. From the 13 ongoing RCTs, 3 have been halted, one has not started, one has unknown status and eight will end between 2016 - 2020. Conclusion Evidence favours a combination of the standard therapy with endovascular thrombectomy. The selection criteria however limit the number of people who can benefit. Further studies are needed to prove its cost-effectiveness. |
| format | Article |
| id | doaj-art-23bf7a10bb0e471bb5167d64fabf8579 |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-23bf7a10bb0e471bb5167d64fabf85792025-08-20T01:58:51ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272015-01-0100010.1590/0004-282X20150182S0004-282X2015005010102Endovascular thrombectomy for the treatment of acute ischemic strokeCleusa P. FerriAnna BuehlerUri Adrian Prync FlatoPaulo Puglia JuniorJefferson G. FernandesABSTRACT Few patients benefit from the current standard treatment for acute ischemic stroke (AIS), encouraging the development of new treatments. Objective To systematically review the literature on the efficacy and/or safety of endovascular thrombectomy in AIS compared to standard treatment and to identify ongoing randomized controlled trials (RCTs). Method Searches for RCTs were performed in Medline/Embase, and for ongoing trials: International Clinical Trial Registry Platform, Clinicaltrials.gov and ISRCTN registry (to June 15th, 2015). Results From the eight published RCTs, five showed the superiority of treatment that includes thrombectomy compared to standard care alone. From the 13 ongoing RCTs, 3 have been halted, one has not started, one has unknown status and eight will end between 2016 - 2020. Conclusion Evidence favours a combination of the standard therapy with endovascular thrombectomy. The selection criteria however limit the number of people who can benefit. Further studies are needed to prove its cost-effectiveness.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015005010102&lng=en&tlng=enacidente vascular cerebraltrombectomiarevisão sistemáticaensaios clínicos randomizados controlados |
| spellingShingle | Cleusa P. Ferri Anna Buehler Uri Adrian Prync Flato Paulo Puglia Junior Jefferson G. Fernandes Endovascular thrombectomy for the treatment of acute ischemic stroke Arquivos de Neuro-Psiquiatria acidente vascular cerebral trombectomia revisão sistemática ensaios clínicos randomizados controlados |
| title | Endovascular thrombectomy for the treatment of acute ischemic stroke |
| title_full | Endovascular thrombectomy for the treatment of acute ischemic stroke |
| title_fullStr | Endovascular thrombectomy for the treatment of acute ischemic stroke |
| title_full_unstemmed | Endovascular thrombectomy for the treatment of acute ischemic stroke |
| title_short | Endovascular thrombectomy for the treatment of acute ischemic stroke |
| title_sort | endovascular thrombectomy for the treatment of acute ischemic stroke |
| topic | acidente vascular cerebral trombectomia revisão sistemática ensaios clínicos randomizados controlados |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015005010102&lng=en&tlng=en |
| work_keys_str_mv | AT cleusapferri endovascularthrombectomyforthetreatmentofacuteischemicstroke AT annabuehler endovascularthrombectomyforthetreatmentofacuteischemicstroke AT uriadrianpryncflato endovascularthrombectomyforthetreatmentofacuteischemicstroke AT paulopugliajunior endovascularthrombectomyforthetreatmentofacuteischemicstroke AT jeffersongfernandes endovascularthrombectomyforthetreatmentofacuteischemicstroke |