Practical and Compact Guided Mode Resonance Sensing System for Highly Sensitive Real-Time Detection
Guided mode resonance (GMR) sensors are known for their ultrasensitive and label-free detection, achieved by assessing refractive index (RI) variations on grating surfaces. However, conventional systems often require manual adjustments, which limits their practical applicability. Therefore, this stu...
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MDPI AG
2025-06-01
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| author | Yen-Song Chen Devesh Barshilia Chia-Jui Hsieh Hsun-Yuan Li Wen-Hsin Hsieh Guo-En Chang |
| author_facet | Yen-Song Chen Devesh Barshilia Chia-Jui Hsieh Hsun-Yuan Li Wen-Hsin Hsieh Guo-En Chang |
| author_sort | Yen-Song Chen |
| collection | DOAJ |
| description | Guided mode resonance (GMR) sensors are known for their ultrasensitive and label-free detection, achieved by assessing refractive index (RI) variations on grating surfaces. However, conventional systems often require manual adjustments, which limits their practical applicability. Therefore, this study enhances the practicality of GMR sensors by introducing an optimized detection system based on the Jones matrix method. In addition, finite element method simulations were performed to optimize the GMR sensor structure parameter. The GMR sensor chip consists of three main components: a cyclic olefin copolymer (COC) substrate with a one-dimensional grating structure of a period of ~295 nm, a height of ~100 nm, and a ~130 nm thick TiO<sub>2</sub> waveguide layer that enhances the light confinement; an integrated COC microfluidic module featuring a microchannel; and flexible tubes for efficient sample handling. A GMR sensor in conjunction with a specially designed system was used to perform RI measurements across varying concentrations of sucrose. The results demonstrate its exceptional performance, with a normalized sensitivity (<i>S</i><sub>n</sub>) and RI resolution (<i>R</i><sub>s</sub>) of 0.4 RIU<sup>−1</sup> and 8.15 × 10<sup>−5</sup> RIU, respectively. The proposed detection system not only offers improved user-friendliness and cost efficiency but also delivers an enhanced performance, making it ideal for scientific and industrial applications, including biosensing and optical metrology, where precise polarization control is crucial. |
| format | Article |
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| institution | Kabale University |
| issn | 1424-8220 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
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| series | Sensors |
| spelling | doaj-art-23b3c58d5b6b43e0931d7c95ef8b1bc12025-08-20T03:29:02ZengMDPI AGSensors1424-82202025-06-012513401910.3390/s25134019Practical and Compact Guided Mode Resonance Sensing System for Highly Sensitive Real-Time DetectionYen-Song Chen0Devesh Barshilia1Chia-Jui Hsieh2Hsun-Yuan Li3Wen-Hsin Hsieh4Guo-En Chang5Department of Mechanical Engineering, and Advanced Institute of Manufacturing with High-Tech Innovations (AIM-HI), National Chung Cheng University, Chiayi 62102, TaiwanDepartment of Mechanical Engineering, and Advanced Institute of Manufacturing with High-Tech Innovations (AIM-HI), National Chung Cheng University, Chiayi 62102, TaiwanDepartment of Mechanical Engineering, and Advanced Institute of Manufacturing with High-Tech Innovations (AIM-HI), National Chung Cheng University, Chiayi 62102, TaiwanDepartment of Mechanical Engineering, and Advanced Institute of Manufacturing with High-Tech Innovations (AIM-HI), National Chung Cheng University, Chiayi 62102, TaiwanDepartment of Mechanical Engineering, and Advanced Institute of Manufacturing with High-Tech Innovations (AIM-HI), National Chung Cheng University, Chiayi 62102, TaiwanDepartment of Mechanical Engineering, and Advanced Institute of Manufacturing with High-Tech Innovations (AIM-HI), National Chung Cheng University, Chiayi 62102, TaiwanGuided mode resonance (GMR) sensors are known for their ultrasensitive and label-free detection, achieved by assessing refractive index (RI) variations on grating surfaces. However, conventional systems often require manual adjustments, which limits their practical applicability. Therefore, this study enhances the practicality of GMR sensors by introducing an optimized detection system based on the Jones matrix method. In addition, finite element method simulations were performed to optimize the GMR sensor structure parameter. The GMR sensor chip consists of three main components: a cyclic olefin copolymer (COC) substrate with a one-dimensional grating structure of a period of ~295 nm, a height of ~100 nm, and a ~130 nm thick TiO<sub>2</sub> waveguide layer that enhances the light confinement; an integrated COC microfluidic module featuring a microchannel; and flexible tubes for efficient sample handling. A GMR sensor in conjunction with a specially designed system was used to perform RI measurements across varying concentrations of sucrose. The results demonstrate its exceptional performance, with a normalized sensitivity (<i>S</i><sub>n</sub>) and RI resolution (<i>R</i><sub>s</sub>) of 0.4 RIU<sup>−1</sup> and 8.15 × 10<sup>−5</sup> RIU, respectively. The proposed detection system not only offers improved user-friendliness and cost efficiency but also delivers an enhanced performance, making it ideal for scientific and industrial applications, including biosensing and optical metrology, where precise polarization control is crucial.https://www.mdpi.com/1424-8220/25/13/4019real-time detectionguided mode resonanceoptical detection systemJones matrixrefractive index sensing |
| spellingShingle | Yen-Song Chen Devesh Barshilia Chia-Jui Hsieh Hsun-Yuan Li Wen-Hsin Hsieh Guo-En Chang Practical and Compact Guided Mode Resonance Sensing System for Highly Sensitive Real-Time Detection Sensors real-time detection guided mode resonance optical detection system Jones matrix refractive index sensing |
| title | Practical and Compact Guided Mode Resonance Sensing System for Highly Sensitive Real-Time Detection |
| title_full | Practical and Compact Guided Mode Resonance Sensing System for Highly Sensitive Real-Time Detection |
| title_fullStr | Practical and Compact Guided Mode Resonance Sensing System for Highly Sensitive Real-Time Detection |
| title_full_unstemmed | Practical and Compact Guided Mode Resonance Sensing System for Highly Sensitive Real-Time Detection |
| title_short | Practical and Compact Guided Mode Resonance Sensing System for Highly Sensitive Real-Time Detection |
| title_sort | practical and compact guided mode resonance sensing system for highly sensitive real time detection |
| topic | real-time detection guided mode resonance optical detection system Jones matrix refractive index sensing |
| url | https://www.mdpi.com/1424-8220/25/13/4019 |
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