A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies

A 41-year-old woman, who underwent breast resection for cancer of the right breast and adjuvant chemotherapy 2 years ago, was admitted to our hospital due to shortness of breath upon exertion. High-resolution computed tomography of the chest showed small nodular opacities in the peribronchiolar area...

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Main Authors: Atsushi Kitamura, Naoki Nishimura, Torahiko Jinta, Rika Suda, Yasuhiko Yamano, Genta Ishikawa, Yutaka Tomishima, Tsuyoshi Hamaoka, Koyu Suzuki, Naohiko Chohnabayashi
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2013/259080
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author Atsushi Kitamura
Naoki Nishimura
Torahiko Jinta
Rika Suda
Yasuhiko Yamano
Genta Ishikawa
Yutaka Tomishima
Tsuyoshi Hamaoka
Koyu Suzuki
Naohiko Chohnabayashi
author_facet Atsushi Kitamura
Naoki Nishimura
Torahiko Jinta
Rika Suda
Yasuhiko Yamano
Genta Ishikawa
Yutaka Tomishima
Tsuyoshi Hamaoka
Koyu Suzuki
Naohiko Chohnabayashi
author_sort Atsushi Kitamura
collection DOAJ
description A 41-year-old woman, who underwent breast resection for cancer of the right breast and adjuvant chemotherapy 2 years ago, was admitted to our hospital due to shortness of breath upon exertion. High-resolution computed tomography of the chest showed small nodular opacities in the peribronchiolar area in both lungs, as well as mediastinal and hilar lymphadenopathy. A transbronchial lung biopsy revealed breast cancer metastasis and pulmonary tumor thrombotic microangiopathy (PTTM). Treatment of PTTM is rarely reported due to the difficulty of antemortem diagnosis; however, the patient was effectively treated with chemotherapy and oxygen and anticoagulation therapies for 3 months.
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institution Kabale University
issn 2090-6846
2090-6854
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Case Reports in Pulmonology
spelling doaj-art-23ae50ebd5b746a78c1165e72fa6260a2025-02-03T01:28:00ZengWileyCase Reports in Pulmonology2090-68462090-68542013-01-01201310.1155/2013/259080259080A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation TherapiesAtsushi Kitamura0Naoki Nishimura1Torahiko Jinta2Rika Suda3Yasuhiko Yamano4Genta Ishikawa5Yutaka Tomishima6Tsuyoshi Hamaoka7Koyu Suzuki8Naohiko Chohnabayashi9Division of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Breast Surgical Oncology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pathology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanA 41-year-old woman, who underwent breast resection for cancer of the right breast and adjuvant chemotherapy 2 years ago, was admitted to our hospital due to shortness of breath upon exertion. High-resolution computed tomography of the chest showed small nodular opacities in the peribronchiolar area in both lungs, as well as mediastinal and hilar lymphadenopathy. A transbronchial lung biopsy revealed breast cancer metastasis and pulmonary tumor thrombotic microangiopathy (PTTM). Treatment of PTTM is rarely reported due to the difficulty of antemortem diagnosis; however, the patient was effectively treated with chemotherapy and oxygen and anticoagulation therapies for 3 months.http://dx.doi.org/10.1155/2013/259080
spellingShingle Atsushi Kitamura
Naoki Nishimura
Torahiko Jinta
Rika Suda
Yasuhiko Yamano
Genta Ishikawa
Yutaka Tomishima
Tsuyoshi Hamaoka
Koyu Suzuki
Naohiko Chohnabayashi
A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies
Case Reports in Pulmonology
title A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies
title_full A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies
title_fullStr A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies
title_full_unstemmed A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies
title_short A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies
title_sort case of pulmonary tumor thrombotic microangiopathy diagnosed by transbronchial lung biopsy and treated with chemotherapy and long term oxygen and anticoagulation therapies
url http://dx.doi.org/10.1155/2013/259080
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