A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies
A 41-year-old woman, who underwent breast resection for cancer of the right breast and adjuvant chemotherapy 2 years ago, was admitted to our hospital due to shortness of breath upon exertion. High-resolution computed tomography of the chest showed small nodular opacities in the peribronchiolar area...
Saved in:
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
|
Series: | Case Reports in Pulmonology |
Online Access: | http://dx.doi.org/10.1155/2013/259080 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832560231521976320 |
---|---|
author | Atsushi Kitamura Naoki Nishimura Torahiko Jinta Rika Suda Yasuhiko Yamano Genta Ishikawa Yutaka Tomishima Tsuyoshi Hamaoka Koyu Suzuki Naohiko Chohnabayashi |
author_facet | Atsushi Kitamura Naoki Nishimura Torahiko Jinta Rika Suda Yasuhiko Yamano Genta Ishikawa Yutaka Tomishima Tsuyoshi Hamaoka Koyu Suzuki Naohiko Chohnabayashi |
author_sort | Atsushi Kitamura |
collection | DOAJ |
description | A 41-year-old woman, who underwent breast resection for cancer of the right breast and adjuvant chemotherapy 2 years ago, was admitted to our hospital due to shortness of breath upon exertion. High-resolution computed tomography of the chest showed small nodular opacities in the peribronchiolar area in both lungs, as well as mediastinal and hilar lymphadenopathy. A transbronchial lung biopsy revealed breast cancer metastasis and pulmonary tumor thrombotic microangiopathy (PTTM). Treatment of PTTM is rarely reported due to the difficulty of antemortem diagnosis; however, the patient was effectively treated with chemotherapy and oxygen and anticoagulation therapies for 3 months. |
format | Article |
id | doaj-art-23ae50ebd5b746a78c1165e72fa6260a |
institution | Kabale University |
issn | 2090-6846 2090-6854 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Pulmonology |
spelling | doaj-art-23ae50ebd5b746a78c1165e72fa6260a2025-02-03T01:28:00ZengWileyCase Reports in Pulmonology2090-68462090-68542013-01-01201310.1155/2013/259080259080A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation TherapiesAtsushi Kitamura0Naoki Nishimura1Torahiko Jinta2Rika Suda3Yasuhiko Yamano4Genta Ishikawa5Yutaka Tomishima6Tsuyoshi Hamaoka7Koyu Suzuki8Naohiko Chohnabayashi9Division of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Breast Surgical Oncology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pathology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanDivision of Pulmonary Medicine, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, JapanA 41-year-old woman, who underwent breast resection for cancer of the right breast and adjuvant chemotherapy 2 years ago, was admitted to our hospital due to shortness of breath upon exertion. High-resolution computed tomography of the chest showed small nodular opacities in the peribronchiolar area in both lungs, as well as mediastinal and hilar lymphadenopathy. A transbronchial lung biopsy revealed breast cancer metastasis and pulmonary tumor thrombotic microangiopathy (PTTM). Treatment of PTTM is rarely reported due to the difficulty of antemortem diagnosis; however, the patient was effectively treated with chemotherapy and oxygen and anticoagulation therapies for 3 months.http://dx.doi.org/10.1155/2013/259080 |
spellingShingle | Atsushi Kitamura Naoki Nishimura Torahiko Jinta Rika Suda Yasuhiko Yamano Genta Ishikawa Yutaka Tomishima Tsuyoshi Hamaoka Koyu Suzuki Naohiko Chohnabayashi A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies Case Reports in Pulmonology |
title | A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies |
title_full | A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies |
title_fullStr | A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies |
title_full_unstemmed | A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies |
title_short | A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies |
title_sort | case of pulmonary tumor thrombotic microangiopathy diagnosed by transbronchial lung biopsy and treated with chemotherapy and long term oxygen and anticoagulation therapies |
url | http://dx.doi.org/10.1155/2013/259080 |
work_keys_str_mv | AT atsushikitamura acaseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT naokinishimura acaseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT torahikojinta acaseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT rikasuda acaseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT yasuhikoyamano acaseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT gentaishikawa acaseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT yutakatomishima acaseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT tsuyoshihamaoka acaseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT koyusuzuki acaseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT naohikochohnabayashi acaseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT atsushikitamura caseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT naokinishimura caseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT torahikojinta caseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT rikasuda caseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT yasuhikoyamano caseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT gentaishikawa caseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT yutakatomishima caseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT tsuyoshihamaoka caseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT koyusuzuki caseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies AT naohikochohnabayashi caseofpulmonarytumorthromboticmicroangiopathydiagnosedbytransbronchiallungbiopsyandtreatedwithchemotherapyandlongtermoxygenandanticoagulationtherapies |