Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila.

Legionella pneumophila is a gram-negative bacterial pathogen that replicates in host macrophages and causes a severe pneumonia called Legionnaires' Disease. The innate immune response to L. pneumophila remains poorly understood. Here we focused on identifying host and bacterial factors involved...

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Bibliographic Details
Main Authors: Kathryn M Monroe, Sarah M McWhirter, Russell E Vance
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000665&type=printable
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