Gastroscope Application in Difficult Colonoscopy: An Effective Alternative for Patients with Gynecologic Oncology
Background: Whole-colon examination is crucial for patients with gynecologic oncology, which somehow presents challenges in some cases. This study is aiming to investigate the effectiveness of gastroscope applied in difficult colonoscopy among such patients. Methods: Patients with gynecologic oncolo...
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| Format: | Article |
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IMR Press
2024-08-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
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| Online Access: | https://www.imrpress.com/journal/CEOG/51/8/10.31083/j.ceog5108192 |
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| author | Linna Luo Wei Qiao Xinxin Huang Yin Li Jianjun Li Wencheng Tan Longjun He |
| author_facet | Linna Luo Wei Qiao Xinxin Huang Yin Li Jianjun Li Wencheng Tan Longjun He |
| author_sort | Linna Luo |
| collection | DOAJ |
| description | Background: Whole-colon examination is crucial for patients with gynecologic oncology, which somehow presents challenges in some cases. This study is aiming to investigate the effectiveness of gastroscope applied in difficult colonoscopy among such patients. Methods: Patients with gynecologic oncology who underwent colon examination were assessed and categorized into two groups, gastroscope replacement group (GR-group) and normal colonoscopy group (NC-group). Gastroscope was applied in the challenging cases within GR-group following unsuccessful attempts for colonoscopy. The assessment encompassed various features, including body mass index (BMI), nutritional indicators, previous therapeutic history, and the number and size of gynecologic oncology. A multivariate analysis was performed to screen out high-risk features for difficult colonoscopy, and a model was developed to evaluate the appropriateness of gastroscope application in such instances. Decision curve analysis was conducted to evaluate the clinical usefulness of the model. Results: We retrospectively collected the clinical characteristics of 171 patients with gynecologic oncology who underwent colon examinations, with 19 cases and 20 cases of difficult colonoscopy in GR-group and NC-group, respectively. The success rate of passing through the narrow site was 63% for the GR-group and 60% for the NC-group (p = 1.000). High risk factors of difficult colonoscopy included a BMI ≤18 kg/m2 (p = 0.03) and post-treatment status (p < 0.01). The evaluation model, constructed from clinical features, demonstrated excellent discrimination with an area under curve (AUC) of 0.86, offering significant net benefits to the validation group. Conclusions: A low BMI and post-treatment status emerged as independent risk factors for difficult colonoscopy in patients with gynecologic oncology. In such cases, gastroscope proved to be an effective and reliable alternative for the colon examination. The current findings are promising to be put into clinical use after verification by large-scale prospective studies. |
| format | Article |
| id | doaj-art-23a22de28d9043cd83088d90c7a4a47c |
| institution | DOAJ |
| issn | 0390-6663 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj-art-23a22de28d9043cd83088d90c7a4a47c2025-08-20T03:03:42ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632024-08-0151819210.31083/j.ceog5108192S0390-6663(24)02427-8Gastroscope Application in Difficult Colonoscopy: An Effective Alternative for Patients with Gynecologic OncologyLinna Luo0Wei Qiao1Xinxin Huang2Yin Li3Jianjun Li4Wencheng Tan5Longjun He6Department of Endoscopy, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Guangdong Provincial Clinical Research Center for Cancer, 510060 Guangzhou, Guangdong, ChinaDepartment of Endoscopy, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Guangdong Provincial Clinical Research Center for Cancer, 510060 Guangzhou, Guangdong, ChinaDepartment of Endoscopy, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Guangdong Provincial Clinical Research Center for Cancer, 510060 Guangzhou, Guangdong, ChinaDepartment of Endoscopy, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Guangdong Provincial Clinical Research Center for Cancer, 510060 Guangzhou, Guangdong, ChinaDepartment of Endoscopy, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Guangdong Provincial Clinical Research Center for Cancer, 510060 Guangzhou, Guangdong, ChinaDepartment of Endoscopy, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Guangdong Provincial Clinical Research Center for Cancer, 510060 Guangzhou, Guangdong, ChinaDepartment of Endoscopy, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Guangdong Provincial Clinical Research Center for Cancer, 510060 Guangzhou, Guangdong, ChinaBackground: Whole-colon examination is crucial for patients with gynecologic oncology, which somehow presents challenges in some cases. This study is aiming to investigate the effectiveness of gastroscope applied in difficult colonoscopy among such patients. Methods: Patients with gynecologic oncology who underwent colon examination were assessed and categorized into two groups, gastroscope replacement group (GR-group) and normal colonoscopy group (NC-group). Gastroscope was applied in the challenging cases within GR-group following unsuccessful attempts for colonoscopy. The assessment encompassed various features, including body mass index (BMI), nutritional indicators, previous therapeutic history, and the number and size of gynecologic oncology. A multivariate analysis was performed to screen out high-risk features for difficult colonoscopy, and a model was developed to evaluate the appropriateness of gastroscope application in such instances. Decision curve analysis was conducted to evaluate the clinical usefulness of the model. Results: We retrospectively collected the clinical characteristics of 171 patients with gynecologic oncology who underwent colon examinations, with 19 cases and 20 cases of difficult colonoscopy in GR-group and NC-group, respectively. The success rate of passing through the narrow site was 63% for the GR-group and 60% for the NC-group (p = 1.000). High risk factors of difficult colonoscopy included a BMI ≤18 kg/m2 (p = 0.03) and post-treatment status (p < 0.01). The evaluation model, constructed from clinical features, demonstrated excellent discrimination with an area under curve (AUC) of 0.86, offering significant net benefits to the validation group. Conclusions: A low BMI and post-treatment status emerged as independent risk factors for difficult colonoscopy in patients with gynecologic oncology. In such cases, gastroscope proved to be an effective and reliable alternative for the colon examination. The current findings are promising to be put into clinical use after verification by large-scale prospective studies.https://www.imrpress.com/journal/CEOG/51/8/10.31083/j.ceog5108192gynecologic oncologydifficult colonoscopygastroscope |
| spellingShingle | Linna Luo Wei Qiao Xinxin Huang Yin Li Jianjun Li Wencheng Tan Longjun He Gastroscope Application in Difficult Colonoscopy: An Effective Alternative for Patients with Gynecologic Oncology Clinical and Experimental Obstetrics & Gynecology gynecologic oncology difficult colonoscopy gastroscope |
| title | Gastroscope Application in Difficult Colonoscopy: An Effective Alternative for Patients with Gynecologic Oncology |
| title_full | Gastroscope Application in Difficult Colonoscopy: An Effective Alternative for Patients with Gynecologic Oncology |
| title_fullStr | Gastroscope Application in Difficult Colonoscopy: An Effective Alternative for Patients with Gynecologic Oncology |
| title_full_unstemmed | Gastroscope Application in Difficult Colonoscopy: An Effective Alternative for Patients with Gynecologic Oncology |
| title_short | Gastroscope Application in Difficult Colonoscopy: An Effective Alternative for Patients with Gynecologic Oncology |
| title_sort | gastroscope application in difficult colonoscopy an effective alternative for patients with gynecologic oncology |
| topic | gynecologic oncology difficult colonoscopy gastroscope |
| url | https://www.imrpress.com/journal/CEOG/51/8/10.31083/j.ceog5108192 |
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