Multifunctional Analysis of CD4+ T-Cell Response as Immune-Based Model for Tuberculosis Detection

Multifunctional Analysis of CD4+ T-Cell Response as Immune-Based Model for Tuberculosis Detection

Mono- and multifunctional specific CD4+ and CD8+ T-cell responses were evaluated to improve the immune-based detection of active tuberculosis (TB) and latent infection (LTBI). We applied flow cytometry to investigate cytokines profile (IFN-γ, TNF-α, and IL-2) of T cells after stimulation with TB ant...

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Main Authors: Miriam Lichtner, Claudia Mascia, Ilaria Sauzullo, Fabio Mengoni, Serena Vita, Raffaella Marocco, Valeria Belvisi, Gianluca Russo, Vincenzo Vullo, Claudio M. Mastroianni
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2015/217287
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