Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Stevens-Johnson syndrome and toxic epidermal necrolysis are severe mucocutaneous rare diseases with high morbid mortality characterized by generalized epidermal necrosis and skin detachment; They are distinguished from each other due to the extent of skin that is affected. Drugs are the main trigger...

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Main Authors: Jeanneth Elizabeth Jami Carrera, John Sebastián Carvajal Gavilanes, Karen Gabriela Sulca Espín, Dennis Alexander Montenegro Montenegro
Format: Article
Language:Spanish
Published: Centro Provincial de Información de Ciencias Médicas. Cienfuegos 2024-11-01
Series:Medisur
Subjects:
Online Access:http://medisur.sld.cu/index.php/medisur/article/view/45303
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author Jeanneth Elizabeth Jami Carrera
John Sebastián Carvajal Gavilanes
Karen Gabriela Sulca Espín
Dennis Alexander Montenegro Montenegro
author_facet Jeanneth Elizabeth Jami Carrera
John Sebastián Carvajal Gavilanes
Karen Gabriela Sulca Espín
Dennis Alexander Montenegro Montenegro
author_sort Jeanneth Elizabeth Jami Carrera
collection DOAJ
description Stevens-Johnson syndrome and toxic epidermal necrolysis are severe mucocutaneous rare diseases with high morbid mortality characterized by generalized epidermal necrosis and skin detachment; They are distinguished from each other due to the extent of skin that is affected. Drugs are the main trigger factor, usually in the first weeks of treatment. These pathologies can be fatal when more than 60 % of the body surface is affected. The objective of the research was to describe distinctive clinical characteristics, underlying triggers and main multisystem manifestations through an updated analysis of Stevens-Johnson syndrome and toxic epidermal necrolysis. It is essential to optimize the prognosis and mitigate the possible complications associated with these medical conditions of high complexity.
format Article
id doaj-art-23949239d07f403e8db3973b92595a3a
institution Kabale University
issn 1727-897X
language Spanish
publishDate 2024-11-01
publisher Centro Provincial de Información de Ciencias Médicas. Cienfuegos
record_format Article
series Medisur
spelling doaj-art-23949239d07f403e8db3973b92595a3a2025-01-30T21:29:03ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2024-11-01226118711942586Stevens-Johnson Syndrome and Toxic Epidermal NecrolysisJeanneth Elizabeth Jami Carrera0John Sebastián Carvajal Gavilanes1Karen Gabriela Sulca Espín2Dennis Alexander Montenegro Montenegro3Universidad Regional Autónoma de los Andes. Ambato. Ecuador.Universidad Regional Autónoma de los Andes. Ambato. Ecuador.Universidad Regional Autónoma de los Andes. Ambato. Ecuador.Universidad Regional Autónoma de los Andes. Ambato. Ecuador.Stevens-Johnson syndrome and toxic epidermal necrolysis are severe mucocutaneous rare diseases with high morbid mortality characterized by generalized epidermal necrosis and skin detachment; They are distinguished from each other due to the extent of skin that is affected. Drugs are the main trigger factor, usually in the first weeks of treatment. These pathologies can be fatal when more than 60 % of the body surface is affected. The objective of the research was to describe distinctive clinical characteristics, underlying triggers and main multisystem manifestations through an updated analysis of Stevens-Johnson syndrome and toxic epidermal necrolysis. It is essential to optimize the prognosis and mitigate the possible complications associated with these medical conditions of high complexity.http://medisur.sld.cu/index.php/medisur/article/view/45303síndrome de stevens-johnsonsepsisqueratinocitos
spellingShingle Jeanneth Elizabeth Jami Carrera
John Sebastián Carvajal Gavilanes
Karen Gabriela Sulca Espín
Dennis Alexander Montenegro Montenegro
Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Medisur
síndrome de stevens-johnson
sepsis
queratinocitos
title Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
title_full Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
title_fullStr Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
title_full_unstemmed Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
title_short Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
title_sort stevens johnson syndrome and toxic epidermal necrolysis
topic síndrome de stevens-johnson
sepsis
queratinocitos
url http://medisur.sld.cu/index.php/medisur/article/view/45303
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AT johnsebastiancarvajalgavilanes stevensjohnsonsyndromeandtoxicepidermalnecrolysis
AT karengabrielasulcaespin stevensjohnsonsyndromeandtoxicepidermalnecrolysis
AT dennisalexandermontenegromontenegro stevensjohnsonsyndromeandtoxicepidermalnecrolysis