MicroRNA therapy for infected wounds

Abstract A novel approach for identification of functional miRNAs in skin wounds reveals miR‐223 as a key regulator of inflammation during tissue repair. The findings suggest targeting of miR‐233 as an effective strategy to enhance neutrophil activation after bacterial infection and to improve heali...

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Main Authors: Paul Hiebert, Sabine Werner
Format: Article
Language:English
Published: Springer Nature 2018-09-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.201809574
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author Paul Hiebert
Sabine Werner
author_facet Paul Hiebert
Sabine Werner
author_sort Paul Hiebert
collection DOAJ
description Abstract A novel approach for identification of functional miRNAs in skin wounds reveals miR‐223 as a key regulator of inflammation during tissue repair. The findings suggest targeting of miR‐233 as an effective strategy to enhance neutrophil activation after bacterial infection and to improve healing of infected wounds.
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issn 1757-4676
1757-4684
language English
publishDate 2018-09-01
publisher Springer Nature
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series EMBO Molecular Medicine
spelling doaj-art-2389bbc2d8bd48118f96ce47b9d8e0c52025-08-20T02:11:29ZengSpringer NatureEMBO Molecular Medicine1757-46761757-46842018-09-0110101310.15252/emmm.201809574MicroRNA therapy for infected woundsPaul Hiebert0Sabine Werner1Department of Biology, Institute of Molecular Health Sciences, Swiss Federal Institute for Technology (ETH) ZurichDepartment of Biology, Institute of Molecular Health Sciences, Swiss Federal Institute for Technology (ETH) ZurichAbstract A novel approach for identification of functional miRNAs in skin wounds reveals miR‐223 as a key regulator of inflammation during tissue repair. The findings suggest targeting of miR‐233 as an effective strategy to enhance neutrophil activation after bacterial infection and to improve healing of infected wounds.https://doi.org/10.15252/emmm.201809574
spellingShingle Paul Hiebert
Sabine Werner
MicroRNA therapy for infected wounds
EMBO Molecular Medicine
title MicroRNA therapy for infected wounds
title_full MicroRNA therapy for infected wounds
title_fullStr MicroRNA therapy for infected wounds
title_full_unstemmed MicroRNA therapy for infected wounds
title_short MicroRNA therapy for infected wounds
title_sort microrna therapy for infected wounds
url https://doi.org/10.15252/emmm.201809574
work_keys_str_mv AT paulhiebert micrornatherapyforinfectedwounds
AT sabinewerner micrornatherapyforinfectedwounds