Clinical Efficacy of Enteral Saline Solution When Used as Part of Combined Treatment for Various Forms of Acute Pancreatitis

The article presents the results of a retrospective study of the effectiveness of intestinal lavage with enteral saline solution for the treatment of dynamic intestinal obstruction in acute forms of pancreatitis and pancreonecrosis. The objective of this study is to improve treatment results in pati...

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Main Authors: R. F. Shavaliev, M. M. Minnullin, R. A. Zefirov, R. N. Akhundov, A. Zh. Bayalieva, Sh. D. Gardanov
Format: Article
Language:English
Published: Bashkir State Medical University 2020-01-01
Series:Креативная хирургия и онкология
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Online Access:https://www.surgonco.ru/jour/article/view/431
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author R. F. Shavaliev
M. M. Minnullin
R. A. Zefirov
R. N. Akhundov
A. Zh. Bayalieva
Sh. D. Gardanov
author_facet R. F. Shavaliev
M. M. Minnullin
R. A. Zefirov
R. N. Akhundov
A. Zh. Bayalieva
Sh. D. Gardanov
author_sort R. F. Shavaliev
collection DOAJ
description The article presents the results of a retrospective study of the effectiveness of intestinal lavage with enteral saline solution for the treatment of dynamic intestinal obstruction in acute forms of pancreatitis and pancreonecrosis. The objective of this study is to improve treatment results in patients with intestinal paresis with various forms of acute pancreatitis with the use of intestinal lavage with enteral saline solution.Materials and methods. The study included 81 patients, 56 (69.1 %) males and 25 (30.9 %) females, the age averaging at 59.3 ± 13.4 years. These patients were hospitalized at different time intervals counting from the onset of the disorder, ranging from 24 hours to 7 days. Patients were divided in two groups depending on hospitalisation prior to the first procedure of intestinal lavage providing there was no counterindications.Results and discussion. Prokinetic effect of intestinal lavage in patients with gastrostasis and dynamic bowel obstruction help improve the quality of conservative treatment (up to 78.3 % in 1st group and 37.1 % in 2nd group); avoid open surgical procedures (up to 6.5 % in 1st group, up to 37.1 % in 2nd group), perform minimally invasive procedures to drain confined lesions (15.2 % of patients in 1st group, 42.9 % in 2nd group); eliminate manifestations of gastrostasis within 3 days following IL in both groups. The reduction/elimination of dynamic intestinal obstruction within 24 hours following IL (up to 73.8 % in 1st group, up to 97.1 % in 2nd group) made it possible to start early enteral nutrition within 48 hours (73.9 % in 1st group, up to 42.8 % in 2nd group).Conclusions. Early use of intestinal lavage in the complex therapy of acute forms of pancreatitis is safe and effective. It reduces the number of purulent-septic complications, prevents the development of multiple organ failure, reduces the overall mortality, prepares the intestine for early enteral nutrition.
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series Креативная хирургия и онкология
spelling doaj-art-237554c8e9aa42c8af014aa7fb77f7892025-08-20T02:53:30ZengBashkir State Medical UniversityКреативная хирургия и онкология2076-30932307-05012020-01-019425426010.24060/2076-3093-2019-9-4-254-260343Clinical Efficacy of Enteral Saline Solution When Used as Part of Combined Treatment for Various Forms of Acute PancreatitisR. F. Shavaliev0M. M. Minnullin1R. A. Zefirov2R. N. Akhundov3A. Zh. Bayalieva4Sh. D. Gardanov5Republican Clinical HospitalRepublican Clinical HospitalRepublican Clinical Hospital; Kazan State Medical UniversityRepublican Clinical HospitalKazan State Medical UniversityKazan State Medical UniversityThe article presents the results of a retrospective study of the effectiveness of intestinal lavage with enteral saline solution for the treatment of dynamic intestinal obstruction in acute forms of pancreatitis and pancreonecrosis. The objective of this study is to improve treatment results in patients with intestinal paresis with various forms of acute pancreatitis with the use of intestinal lavage with enteral saline solution.Materials and methods. The study included 81 patients, 56 (69.1 %) males and 25 (30.9 %) females, the age averaging at 59.3 ± 13.4 years. These patients were hospitalized at different time intervals counting from the onset of the disorder, ranging from 24 hours to 7 days. Patients were divided in two groups depending on hospitalisation prior to the first procedure of intestinal lavage providing there was no counterindications.Results and discussion. Prokinetic effect of intestinal lavage in patients with gastrostasis and dynamic bowel obstruction help improve the quality of conservative treatment (up to 78.3 % in 1st group and 37.1 % in 2nd group); avoid open surgical procedures (up to 6.5 % in 1st group, up to 37.1 % in 2nd group), perform minimally invasive procedures to drain confined lesions (15.2 % of patients in 1st group, 42.9 % in 2nd group); eliminate manifestations of gastrostasis within 3 days following IL in both groups. The reduction/elimination of dynamic intestinal obstruction within 24 hours following IL (up to 73.8 % in 1st group, up to 97.1 % in 2nd group) made it possible to start early enteral nutrition within 48 hours (73.9 % in 1st group, up to 42.8 % in 2nd group).Conclusions. Early use of intestinal lavage in the complex therapy of acute forms of pancreatitis is safe and effective. It reduces the number of purulent-septic complications, prevents the development of multiple organ failure, reduces the overall mortality, prepares the intestine for early enteral nutrition.https://www.surgonco.ru/jour/article/view/431acute pancreatitispancreonecrosisintestinal obstructionacute intestinal failureintestinal lavageenteral saline solution
spellingShingle R. F. Shavaliev
M. M. Minnullin
R. A. Zefirov
R. N. Akhundov
A. Zh. Bayalieva
Sh. D. Gardanov
Clinical Efficacy of Enteral Saline Solution When Used as Part of Combined Treatment for Various Forms of Acute Pancreatitis
Креативная хирургия и онкология
acute pancreatitis
pancreonecrosis
intestinal obstruction
acute intestinal failure
intestinal lavage
enteral saline solution
title Clinical Efficacy of Enteral Saline Solution When Used as Part of Combined Treatment for Various Forms of Acute Pancreatitis
title_full Clinical Efficacy of Enteral Saline Solution When Used as Part of Combined Treatment for Various Forms of Acute Pancreatitis
title_fullStr Clinical Efficacy of Enteral Saline Solution When Used as Part of Combined Treatment for Various Forms of Acute Pancreatitis
title_full_unstemmed Clinical Efficacy of Enteral Saline Solution When Used as Part of Combined Treatment for Various Forms of Acute Pancreatitis
title_short Clinical Efficacy of Enteral Saline Solution When Used as Part of Combined Treatment for Various Forms of Acute Pancreatitis
title_sort clinical efficacy of enteral saline solution when used as part of combined treatment for various forms of acute pancreatitis
topic acute pancreatitis
pancreonecrosis
intestinal obstruction
acute intestinal failure
intestinal lavage
enteral saline solution
url https://www.surgonco.ru/jour/article/view/431
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