A Very Rare Case of Hypereosinophilic Syndrome Secondary to Natural Killer/T-Cell Lymphoma

Hypereosinophilic syndrome (HES) is a systemic disease characterized by an increased peripheral blood eosinophil count accompanied by systemic organ dysfunction. HES is classified into idiopathic HES, primary (neoplastic) HES (HESN), and secondary (reactive) HES (HESR). In this case report, a patien...

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Main Authors: Takanori Yamamoto, Atsushi Kamijo, Tadao Nakazawa, Kei Nakajima, Keita Kirito, Norio Komatsu, Keisuke Masuyama
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2018/5965029
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author Takanori Yamamoto
Atsushi Kamijo
Tadao Nakazawa
Kei Nakajima
Keita Kirito
Norio Komatsu
Keisuke Masuyama
author_facet Takanori Yamamoto
Atsushi Kamijo
Tadao Nakazawa
Kei Nakajima
Keita Kirito
Norio Komatsu
Keisuke Masuyama
author_sort Takanori Yamamoto
collection DOAJ
description Hypereosinophilic syndrome (HES) is a systemic disease characterized by an increased peripheral blood eosinophil count accompanied by systemic organ dysfunction. HES is classified into idiopathic HES, primary (neoplastic) HES (HESN), and secondary (reactive) HES (HESR). In this case report, a patient who developed peripheral blood eosinophilia and granulation tissue in the pharynx and paranasal sinus, which was initially diagnosed as chronic eosinophilic leukemia (CEL), categorized as HESN, but was eventually identified after the patient had died as natural killer/T-cell (NK/T) lymphoma, nasal type (ENKL), categorized as HESR, is presented. ENKL-induced HES is very rare but must be considered.
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institution OA Journals
issn 2090-6765
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publishDate 2018-01-01
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series Case Reports in Otolaryngology
spelling doaj-art-23718d65469a47b5bac1067d906cfd5b2025-08-20T02:04:14ZengWileyCase Reports in Otolaryngology2090-67652090-67732018-01-01201810.1155/2018/59650295965029A Very Rare Case of Hypereosinophilic Syndrome Secondary to Natural Killer/T-Cell LymphomaTakanori Yamamoto0Atsushi Kamijo1Tadao Nakazawa2Kei Nakajima3Keita Kirito4Norio Komatsu5Keisuke Masuyama6Department of Otorhinolaryngology and Head & Neck Surgery, University of Yamanashi, Yamanashi, JapanDepartment of Otorhinolaryngology and Head & Neck Surgery, University of Yamanashi, Yamanashi, JapanDepartment of Pathology, University of Yamanashi, Yamanashi, JapanDepartment of Hematology and Oncology, University of Yamanashi, Yamanashi, JapanDepartment of Hematology and Oncology, University of Yamanashi, Yamanashi, JapanDepartment of Hematology, Juntendo University School of Medicine, Tokyo, JapanDepartment of Otorhinolaryngology and Head & Neck Surgery, University of Yamanashi, Yamanashi, JapanHypereosinophilic syndrome (HES) is a systemic disease characterized by an increased peripheral blood eosinophil count accompanied by systemic organ dysfunction. HES is classified into idiopathic HES, primary (neoplastic) HES (HESN), and secondary (reactive) HES (HESR). In this case report, a patient who developed peripheral blood eosinophilia and granulation tissue in the pharynx and paranasal sinus, which was initially diagnosed as chronic eosinophilic leukemia (CEL), categorized as HESN, but was eventually identified after the patient had died as natural killer/T-cell (NK/T) lymphoma, nasal type (ENKL), categorized as HESR, is presented. ENKL-induced HES is very rare but must be considered.http://dx.doi.org/10.1155/2018/5965029
spellingShingle Takanori Yamamoto
Atsushi Kamijo
Tadao Nakazawa
Kei Nakajima
Keita Kirito
Norio Komatsu
Keisuke Masuyama
A Very Rare Case of Hypereosinophilic Syndrome Secondary to Natural Killer/T-Cell Lymphoma
Case Reports in Otolaryngology
title A Very Rare Case of Hypereosinophilic Syndrome Secondary to Natural Killer/T-Cell Lymphoma
title_full A Very Rare Case of Hypereosinophilic Syndrome Secondary to Natural Killer/T-Cell Lymphoma
title_fullStr A Very Rare Case of Hypereosinophilic Syndrome Secondary to Natural Killer/T-Cell Lymphoma
title_full_unstemmed A Very Rare Case of Hypereosinophilic Syndrome Secondary to Natural Killer/T-Cell Lymphoma
title_short A Very Rare Case of Hypereosinophilic Syndrome Secondary to Natural Killer/T-Cell Lymphoma
title_sort very rare case of hypereosinophilic syndrome secondary to natural killer t cell lymphoma
url http://dx.doi.org/10.1155/2018/5965029
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