A Very Rare Case of Hypereosinophilic Syndrome Secondary to Natural Killer/T-Cell Lymphoma

Hypereosinophilic syndrome (HES) is a systemic disease characterized by an increased peripheral blood eosinophil count accompanied by systemic organ dysfunction. HES is classified into idiopathic HES, primary (neoplastic) HES (HESN), and secondary (reactive) HES (HESR). In this case report, a patien...

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Bibliographic Details
Main Authors: Takanori Yamamoto, Atsushi Kamijo, Tadao Nakazawa, Kei Nakajima, Keita Kirito, Norio Komatsu, Keisuke Masuyama
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2018/5965029
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Summary:Hypereosinophilic syndrome (HES) is a systemic disease characterized by an increased peripheral blood eosinophil count accompanied by systemic organ dysfunction. HES is classified into idiopathic HES, primary (neoplastic) HES (HESN), and secondary (reactive) HES (HESR). In this case report, a patient who developed peripheral blood eosinophilia and granulation tissue in the pharynx and paranasal sinus, which was initially diagnosed as chronic eosinophilic leukemia (CEL), categorized as HESN, but was eventually identified after the patient had died as natural killer/T-cell (NK/T) lymphoma, nasal type (ENKL), categorized as HESR, is presented. ENKL-induced HES is very rare but must be considered.
ISSN:2090-6765
2090-6773