Coexistence of Tuberculosis and Lophomoniasis in a Patient With Alzheimer's Disease
ABSTRACT The coexistence of lophomoniasis and tuberculosis (TB), both airborne diseases, is relatively uncommon. Co‐infections like these can complicate treatment strategies due to overlapping symptoms and potential drug interactions. We report a rare case of comorbidity involving two pulmonary dise...
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| Format: | Article |
| Language: | English |
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Wiley
2025-06-01
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| Series: | Respirology Case Reports |
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| Online Access: | https://doi.org/10.1002/rcr2.70248 |
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| author | Masoud Maboudi Eissa Soleymani Elham Sadat Banimostafavi Shirafkan Kordi Majidreza Adelani Zakaria Zakariaei Mahdi Fakhar |
| author_facet | Masoud Maboudi Eissa Soleymani Elham Sadat Banimostafavi Shirafkan Kordi Majidreza Adelani Zakaria Zakariaei Mahdi Fakhar |
| author_sort | Masoud Maboudi |
| collection | DOAJ |
| description | ABSTRACT The coexistence of lophomoniasis and tuberculosis (TB), both airborne diseases, is relatively uncommon. Co‐infections like these can complicate treatment strategies due to overlapping symptoms and potential drug interactions. We report a rare case of comorbidity involving two pulmonary diseases, lophomoniasis and TB, in an 82‐year‐old woman with Alzheimer's disease (AD) from northern Iran. Her primary symptoms included weakness, lethargy, dyspnea, sputum production, night sweats, and significant weight loss. Both TB and lophomoniasis can compromise the immune system, potentially worsening the progression or severity of AD by increasing susceptibility to infections or enhancing neuroinflammation. Following the prescription of appropriate drug regimens for both diseases, the patient was discharged from the hospital in stable condition. Overall, it is crucial to consider lophomoniasis in the differential diagnosis of patients with pulmonary tuberculosis, especially in endemic areas where both infections are prevalent, to ensure timely diagnosis and effective management. |
| format | Article |
| id | doaj-art-236f460dd0c04ed0af5947f56b455613 |
| institution | OA Journals |
| issn | 2051-3380 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Respirology Case Reports |
| spelling | doaj-art-236f460dd0c04ed0af5947f56b4556132025-08-20T02:22:05ZengWileyRespirology Case Reports2051-33802025-06-01136n/an/a10.1002/rcr2.70248Coexistence of Tuberculosis and Lophomoniasis in a Patient With Alzheimer's DiseaseMasoud Maboudi0Eissa Soleymani1Elham Sadat Banimostafavi2Shirafkan Kordi3Majidreza Adelani4Zakaria Zakariaei5Mahdi Fakhar6Department of Infectious Diseases, Faculty of Medicine, Antimicrobial Resistance Research Center Mazandaran University of Medical Sciences Sari IranToxoplasmosis Research Center, Communicable Diseases Institute, Department of Parasitology Mazandaran University of Medical Sciences Sari IranDepartment of Radiology Shahid Beheshti Hospital, Qom University of Medical Sciences Qom IranDepartment of Infectious Diseases, Faculty of Medicine, Antimicrobial Resistance Research Center Mazandaran University of Medical Sciences Sari IranDepartment of Internal Ward, Pulmonary and Critical Care Division Mazandaran University of Medical Sciences Sari IranDepartment of Forensic Medicine and Toxicology, Mazandaran Registry Center for Opioids Poisoning, Orthopedic Research Centers Imam Khomeini Hospital, Mazandaran University of Medical Sciences Sari IranToxoplasmosis Research Center, Communicable Diseases Institute, Department of Parasitology Mazandaran University of Medical Sciences Sari IranABSTRACT The coexistence of lophomoniasis and tuberculosis (TB), both airborne diseases, is relatively uncommon. Co‐infections like these can complicate treatment strategies due to overlapping symptoms and potential drug interactions. We report a rare case of comorbidity involving two pulmonary diseases, lophomoniasis and TB, in an 82‐year‐old woman with Alzheimer's disease (AD) from northern Iran. Her primary symptoms included weakness, lethargy, dyspnea, sputum production, night sweats, and significant weight loss. Both TB and lophomoniasis can compromise the immune system, potentially worsening the progression or severity of AD by increasing susceptibility to infections or enhancing neuroinflammation. Following the prescription of appropriate drug regimens for both diseases, the patient was discharged from the hospital in stable condition. Overall, it is crucial to consider lophomoniasis in the differential diagnosis of patients with pulmonary tuberculosis, especially in endemic areas where both infections are prevalent, to ensure timely diagnosis and effective management.https://doi.org/10.1002/rcr2.70248Alzheimer's diseaseLophomonasLophomoniasismetronidazoleMycobacterium |
| spellingShingle | Masoud Maboudi Eissa Soleymani Elham Sadat Banimostafavi Shirafkan Kordi Majidreza Adelani Zakaria Zakariaei Mahdi Fakhar Coexistence of Tuberculosis and Lophomoniasis in a Patient With Alzheimer's Disease Respirology Case Reports Alzheimer's disease Lophomonas Lophomoniasis metronidazole Mycobacterium |
| title | Coexistence of Tuberculosis and Lophomoniasis in a Patient With Alzheimer's Disease |
| title_full | Coexistence of Tuberculosis and Lophomoniasis in a Patient With Alzheimer's Disease |
| title_fullStr | Coexistence of Tuberculosis and Lophomoniasis in a Patient With Alzheimer's Disease |
| title_full_unstemmed | Coexistence of Tuberculosis and Lophomoniasis in a Patient With Alzheimer's Disease |
| title_short | Coexistence of Tuberculosis and Lophomoniasis in a Patient With Alzheimer's Disease |
| title_sort | coexistence of tuberculosis and lophomoniasis in a patient with alzheimer s disease |
| topic | Alzheimer's disease Lophomonas Lophomoniasis metronidazole Mycobacterium |
| url | https://doi.org/10.1002/rcr2.70248 |
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