50 Years of Antibody Numbering Schemes: A Statistical and Structural Evaluation Reveals Key Differences and Limitations

Background: The complementarity-determining region (CDR) of antibodies represents the most diverse region both in terms of sequence and structural characteristics, playing the most critical role in antibody recognition and binding for immune responses. Over the past decades, several numbering scheme...

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Bibliographic Details
Main Authors: Zirui Zhu, Katherine S. Olson, Thomas J. Magliery
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Antibodies
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Online Access:https://www.mdpi.com/2073-4468/13/4/99
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