The Symptoms Get Worse after Pregnancy in Sheehan's Syndrome: A Case Report
Sheehan’s syndrome, which is pituitary necrosis after severe postpartum hemorrhage and hypovolemia, may cause hypopituitarism immediately or several years later, depending on the degree of tissue destruction. We report an unusual case, in which a 55-year-old woman with Sheehan's syndrome got wo...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/271345 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850228033932230656 |
|---|---|
| author | Jingwen Hao Min Liu Zhaohui Mo |
| author_facet | Jingwen Hao Min Liu Zhaohui Mo |
| author_sort | Jingwen Hao |
| collection | DOAJ |
| description | Sheehan’s syndrome, which is pituitary necrosis after severe postpartum hemorrhage and hypovolemia, may cause hypopituitarism immediately or several years later, depending on the degree of tissue destruction. We report an unusual case, in which a 55-year-old woman with Sheehan's syndrome got worse symptoms after spontaneous labor. In 1998, she had severe postpartum hemorrhage and pituitary necrosis during the third delivery, thus it was diagnosed as Sheehan’s syndrome by clinical manifestations, laboratory tests, and magnetic resonance imaging. She was treated by replacement therapy including hydrocortisone and levothyroxine sodium. However, she had the fourth spontaneous pregnancy in 2000 and got worse symptoms after delivery. We carefully concluded that pregnancy provided no evidence against the diagnosis of Sheehan’s syndrome because pregnancy might improve hypopituitarism by stimulating the pituitary remnant to undergo hyperplasia and irritating the placenta to secrete hormone. However, pregnancy might aggravate the symptoms by inducing autoimmunity as well. All in all, early diagnosis and adequate medical treatment are important to provide a good prognosis of Sheehan’s syndrome. |
| format | Article |
| id | doaj-art-23409ab6eeec493a98366cbc4f9cd8d4 |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-23409ab6eeec493a98366cbc4f9cd8d42025-08-20T02:04:39ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/271345271345The Symptoms Get Worse after Pregnancy in Sheehan's Syndrome: A Case ReportJingwen Hao0Min Liu1Zhaohui Mo2Department of Endocrinology, The Third Xiangya Hospital, Central South University, 138 Tongzipo Road, Changsha 410013, Hunan, ChinaDepartment of Endocrinology, The Third Xiangya Hospital, Central South University, 138 Tongzipo Road, Changsha 410013, Hunan, ChinaDepartment of Endocrinology, The Third Xiangya Hospital, Central South University, 138 Tongzipo Road, Changsha 410013, Hunan, ChinaSheehan’s syndrome, which is pituitary necrosis after severe postpartum hemorrhage and hypovolemia, may cause hypopituitarism immediately or several years later, depending on the degree of tissue destruction. We report an unusual case, in which a 55-year-old woman with Sheehan's syndrome got worse symptoms after spontaneous labor. In 1998, she had severe postpartum hemorrhage and pituitary necrosis during the third delivery, thus it was diagnosed as Sheehan’s syndrome by clinical manifestations, laboratory tests, and magnetic resonance imaging. She was treated by replacement therapy including hydrocortisone and levothyroxine sodium. However, she had the fourth spontaneous pregnancy in 2000 and got worse symptoms after delivery. We carefully concluded that pregnancy provided no evidence against the diagnosis of Sheehan’s syndrome because pregnancy might improve hypopituitarism by stimulating the pituitary remnant to undergo hyperplasia and irritating the placenta to secrete hormone. However, pregnancy might aggravate the symptoms by inducing autoimmunity as well. All in all, early diagnosis and adequate medical treatment are important to provide a good prognosis of Sheehan’s syndrome.http://dx.doi.org/10.1155/2012/271345 |
| spellingShingle | Jingwen Hao Min Liu Zhaohui Mo The Symptoms Get Worse after Pregnancy in Sheehan's Syndrome: A Case Report Case Reports in Medicine |
| title | The Symptoms Get Worse after Pregnancy in Sheehan's Syndrome: A Case Report |
| title_full | The Symptoms Get Worse after Pregnancy in Sheehan's Syndrome: A Case Report |
| title_fullStr | The Symptoms Get Worse after Pregnancy in Sheehan's Syndrome: A Case Report |
| title_full_unstemmed | The Symptoms Get Worse after Pregnancy in Sheehan's Syndrome: A Case Report |
| title_short | The Symptoms Get Worse after Pregnancy in Sheehan's Syndrome: A Case Report |
| title_sort | symptoms get worse after pregnancy in sheehan s syndrome a case report |
| url | http://dx.doi.org/10.1155/2012/271345 |
| work_keys_str_mv | AT jingwenhao thesymptomsgetworseafterpregnancyinsheehanssyndromeacasereport AT minliu thesymptomsgetworseafterpregnancyinsheehanssyndromeacasereport AT zhaohuimo thesymptomsgetworseafterpregnancyinsheehanssyndromeacasereport AT jingwenhao symptomsgetworseafterpregnancyinsheehanssyndromeacasereport AT minliu symptomsgetworseafterpregnancyinsheehanssyndromeacasereport AT zhaohuimo symptomsgetworseafterpregnancyinsheehanssyndromeacasereport |