An Unusual Presentation of Herpes Simplex Virus Encephalitis
We present a case of a 65-year-old man with an acute alteration in mental state that was initially diagnosed as a functional psychiatric condition. After extensive workup, herpes simplex virus type 1 (HSV-1) was detected in the patient’s cerebrospinal fluid (CSF) by polymerase chain reaction (PCR),...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/241710 |
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| _version_ | 1850228156719431680 |
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| author | Ray Boyapati George Papadopoulos James Olver Michael Geluk Paul D. R. Johnson |
| author_facet | Ray Boyapati George Papadopoulos James Olver Michael Geluk Paul D. R. Johnson |
| author_sort | Ray Boyapati |
| collection | DOAJ |
| description | We present a case of a 65-year-old man with an acute alteration in mental state that was initially diagnosed as a functional psychiatric condition. After extensive workup, herpes simplex virus type 1 (HSV-1) was detected in the patient’s cerebrospinal fluid (CSF) by polymerase chain reaction (PCR), and he responded rapidly to treatment with acyclovir. The case illustrates the importance of actively excluding organic causes in such patients, the need to have a low threshold of suspicion for HSV encephalitis, and the central role of CSF PCR testing for the diagnosis of HSV encephalitis, even in the absence of CSF biochemical abnormalities. |
| format | Article |
| id | doaj-art-233adb071b0b4a44a4ff67ca40d68f58 |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-233adb071b0b4a44a4ff67ca40d68f582025-08-20T02:04:37ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/241710241710An Unusual Presentation of Herpes Simplex Virus EncephalitisRay Boyapati0George Papadopoulos1James Olver2Michael Geluk3Paul D. R. Johnson4Department of Medicine, Austin Health, Studley Road, Heidelberg, VIC 3084, AustraliaDepartment of Medicine, Austin Health, Studley Road, Heidelberg, VIC 3084, AustraliaDepartment of Psychiatry, Austin Health, Studley Road, Heidelberg, VIC 3084, AustraliaDepartment of Emergency Medicine, Austin Health, Studley Road, Heidelberg, VIC 3084, AustraliaDepartments of Infectious Diseases and Microbiology, Austin Health, Studley Road, Heidelberg, VIC 3084, AustraliaWe present a case of a 65-year-old man with an acute alteration in mental state that was initially diagnosed as a functional psychiatric condition. After extensive workup, herpes simplex virus type 1 (HSV-1) was detected in the patient’s cerebrospinal fluid (CSF) by polymerase chain reaction (PCR), and he responded rapidly to treatment with acyclovir. The case illustrates the importance of actively excluding organic causes in such patients, the need to have a low threshold of suspicion for HSV encephalitis, and the central role of CSF PCR testing for the diagnosis of HSV encephalitis, even in the absence of CSF biochemical abnormalities.http://dx.doi.org/10.1155/2012/241710 |
| spellingShingle | Ray Boyapati George Papadopoulos James Olver Michael Geluk Paul D. R. Johnson An Unusual Presentation of Herpes Simplex Virus Encephalitis Case Reports in Medicine |
| title | An Unusual Presentation of Herpes Simplex Virus Encephalitis |
| title_full | An Unusual Presentation of Herpes Simplex Virus Encephalitis |
| title_fullStr | An Unusual Presentation of Herpes Simplex Virus Encephalitis |
| title_full_unstemmed | An Unusual Presentation of Herpes Simplex Virus Encephalitis |
| title_short | An Unusual Presentation of Herpes Simplex Virus Encephalitis |
| title_sort | unusual presentation of herpes simplex virus encephalitis |
| url | http://dx.doi.org/10.1155/2012/241710 |
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