Lung disease in relation to unique monocyte-macrophage subpopulations induced by combined inhalant endotoxin and collagen-induced arthritis

Lung disease in relation to unique monocyte-macrophage subpopulations induced by combined inhalant endotoxin and collagen-induced arthritis

BackgroundLung disease is the most overrepresented cause of death in rheumatoid arthritis (RA). Animal studies have demonstrated potentiated autoimmunity, arthritis, and profibrotic/inflammatory lung disease with a combination of airborne exposures and collagen-induced arthritis (CIA), a model that...

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Bibliographic Details
Main Authors: Jill A. Poole, Aaron Schwab, Geoffrey M. Thiele, Todd A. Wyatt, Amy J. Nelson, Oliver W. Schanze, Angela Gleason, Michael J. Duryee, Bryant R. England, Ted R. Mikuls
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
lung
autoimmunity
macrophage
monocyte
inflammation
fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1557583/full
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