Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro Analogues

Superparamagnetic Fe3O4 is shown to act as a very efficient catalyst for the one-pot, three-component synthesis of 5,5-disubstituted hexahydropyrimidines and their spiropiperidines. The catalyst is easily recovered by the use of an external magnet and reused in several reactions without any noticeab...

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Main Authors: Fatemeh Janati, Majid M. Heravi, Ahmad Mirshokraie
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2013/214617
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author Fatemeh Janati
Majid M. Heravi
Ahmad Mirshokraie
author_facet Fatemeh Janati
Majid M. Heravi
Ahmad Mirshokraie
author_sort Fatemeh Janati
collection DOAJ
description Superparamagnetic Fe3O4 is shown to act as a very efficient catalyst for the one-pot, three-component synthesis of 5,5-disubstituted hexahydropyrimidines and their spiropiperidines. The catalyst is easily recovered by the use of an external magnet and reused in several reactions without any noticeable loss of activity. The products are obtained in short time and good purity upon separation of the catalyst and evaporation of the volatiles of the reaction mixture.
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institution Kabale University
issn 2090-9063
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publishDate 2013-01-01
publisher Wiley
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series Journal of Chemistry
spelling doaj-art-231dae557e6947a9859a09f66d4328e32025-02-03T01:22:55ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/214617214617Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro AnaloguesFatemeh Janati0Majid M. Heravi1Ahmad Mirshokraie2Department of Chemistry, Faculty of Sciences, Payame Noor University, Mashhad 91735-433, IranDepartment of Chemistry, School of Sciences, Alzahra University, Vanak, Tehran, IranDepartment of Chemistry, Faculty of Sciences, Payame Noor University, Mashhad 91735-433, IranSuperparamagnetic Fe3O4 is shown to act as a very efficient catalyst for the one-pot, three-component synthesis of 5,5-disubstituted hexahydropyrimidines and their spiropiperidines. The catalyst is easily recovered by the use of an external magnet and reused in several reactions without any noticeable loss of activity. The products are obtained in short time and good purity upon separation of the catalyst and evaporation of the volatiles of the reaction mixture.http://dx.doi.org/10.1155/2013/214617
spellingShingle Fatemeh Janati
Majid M. Heravi
Ahmad Mirshokraie
Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro Analogues
Journal of Chemistry
title Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro Analogues
title_full Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro Analogues
title_fullStr Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro Analogues
title_full_unstemmed Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro Analogues
title_short Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro Analogues
title_sort superparamagnetic iron oxide as an efficient catalyst for the one pot solvent free synthesis of 5 5 disubstituted hexahydropyrimidines and their spiro analogues
url http://dx.doi.org/10.1155/2013/214617
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