Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro Analogues

Superparamagnetic Fe3O4 is shown to act as a very efficient catalyst for the one-pot, three-component synthesis of 5,5-disubstituted hexahydropyrimidines and their spiropiperidines. The catalyst is easily recovered by the use of an external magnet and reused in several reactions without any noticeab...

Full description

Saved in:
Bibliographic Details
Main Authors: Fatemeh Janati, Majid M. Heravi, Ahmad Mirshokraie
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2013/214617
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Superparamagnetic Fe3O4 is shown to act as a very efficient catalyst for the one-pot, three-component synthesis of 5,5-disubstituted hexahydropyrimidines and their spiropiperidines. The catalyst is easily recovered by the use of an external magnet and reused in several reactions without any noticeable loss of activity. The products are obtained in short time and good purity upon separation of the catalyst and evaporation of the volatiles of the reaction mixture.
ISSN:2090-9063
2090-9071