Uric acid-induced cardiomyocytic polyamines’ insufficience: a potential mechanism mediates cardiomyocytic injury

Uric acid-induced cardiomyocytic polyamines’ insufficience: a potential mechanism mediates cardiomyocytic injury

IntroductionMaintaining polyamines homeostasis is essential for cardiovascular health, whereas elevated uric acid levels are recognized as a significant risk factor for the onset and progression of cardiovascular diseases. However, the interaction between uric acid and the regulation of polyamine ho...

Full description

Saved in:

Bibliographic Details
Main Authors:	Cuiting Lin, Qiang Zheng, Haiyan Yu, Ting Wu, Lin Chen, Weihao Lin, Jianxin Pang, Yang Yang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Series:	Frontiers in Endocrinology
Subjects:	polyamines uric acid cardiomyocytes spermidine spermine
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1504614/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Plasma Polyamines and Short‐Term Adverse Outcomes Among Patients With Ischemic Stroke: A Prospective Cohort Study
by: Pinni Yang, et al.
Published: (2024-08-01)

Polyamine Content of Enteral Nutrition Formulas: Effect of Daily Intake on the Feeding Tolerance of Patients During the First Week in the Intensive Care Unit
by: Manuel Sánchez, et al.
Published: (2025-01-01)

Polyamine and Isoamylamine Levels in Peripheral Blood Cells and Plasma as Biomarkers of Structural and Functional Alterations in Acute Myocardial Infarction and Chronic Heart Failure Patients
by: José Manuel Rubín, et al.
Published: (2025-06-01)

Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder–Robinson syndrome
by: Tracy Murray Stewart, et al.
Published: (2023-09-01)

NF-E2-related factor 1 suppresses the expression of a spermine oxidase and the production of highly reactive acrolein
by: Tomoaki Hirakawa, et al.
Published: (2025-04-01)

Structure and biological action of analogs and derivatives of biogenic polyamines
by: O. S. Egorov, et al.
Published: (2021-09-01)

Diamine Fungal Inducers of Secondary Metabolism: 1,3-Diaminopropane and Spermidine Trigger Enzymes Involved in β-Alanine and Pantothenic Acid Biosynthesis, Precursors of Phosphopantetheine in the Activation of Multidomain Enzymes
by: Juan Francisco Martín, et al.
Published: (2024-09-01)

Research progress on the microbial metabolism and transport of polyamines and their roles in animal gut homeostasis
by: Chong Zhang, et al.
Published: (2025-04-01)

The Renaissance of Polyamines: New Roles in Crop Yield and Quality Properties in Freshly Fruit
by: Jenifer Puente-Moreno, et al.
Published: (2025-01-01)

Integrative analysis of polyamine metabolism-related genes in gliomas: implications for prognosis and therapy
by: Yujia Zhao, et al.
Published: (2025-07-01)

Novel protocol significantly improving spermidine content in extracts from wheat germ: Aqueous conversion of polyamines into neutral-base form, solubility in ethanol and acid precipitation as phosphate salts
by: Eros D'Amen, et al.
Published: (2025-03-01)

Snyder-Robinson syndrome presenting with learning disability, epilepsy, and osteoporosis: A novel SMS gene variant
by: Megumi Leung, et al.
Published: (2024-01-01)

A Bis(Acridino)-Crown Ether for Recognizing Oligoamines in Spermine Biosynthesis
by: Péter Kisfaludi, et al.
Published: (2024-09-01)

Polyamine metabolism and anti-tumor immunity
by: Jing-Yi Wu, et al.
Published: (2025-02-01)

Danqi soft caspule alleviates myocardial ischemia-reperfusion injury induced cardiomyocyte apoptosis by attenuating mitochondrial fission
by: Ye Yang, et al.
Published: (2025-03-01)

Corrigendum: Danqi soft caspule alleviates myocardial ischemia-reperfusion injury induced cardiomyocyte apoptosis by attenuating mitochondrial fission
by: Ye Yang, et al.
Published: (2025-06-01)

Cardiomyocyte‐Specific Overexpression of Activated Yes‐Associated Protein Modified‐RNA Promotes Cardiomyocyte Proliferation and Myocardial Regeneration
by: Yongyu Wang, et al.
Published: (2024-11-01)

Reprogramming‐derived gene cocktail increases cardiomyocyte proliferation for heart regeneration
by: Yuan‐Yuan Cheng, et al.
Published: (2016-12-01)

Single Nanocrown Electrodes for High‐Quality Intracellular Recording of Cardiomyocytes
by: Ching‐Ting Tsai, et al.
Published: (2025-07-01)

The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastoma
by: Mujahid Azfar, et al.
Published: (2025-03-01)

Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma
by: Jianyan Pan, et al.
Published: (2025-02-01)

Right ventricular volume overload reboots cardiomyocyte proliferation via immune responses
by: Chunxia Zhou, et al.
Published: (2024-11-01)

The involvement of arbuscular mycorrhizal fungi in modulating polyamine metabolism and low-temperature tolerance enhancement in white clover
by: Songyuan Yao, et al.
Published: (2025-06-01)

Elevated levels of Letm1 drives mitochondrial dysfunction and cardiomyocyte stress-mediated apoptosis in cultured cardiomyocytes
by: Anushka Deshpande, et al.
Published: (2025-08-01)

Nanoplastics induces arrhythmia in human stem-cells derived cardiomyocytes
by: Shirley Pei Shan Chia, et al.
Published: (2025-01-01)

Lipid exposure leads to metabolic dysfunction in fetal sheep cardiomyocytes
by: Natasha N. Chattergoon, et al.
Published: (2025-05-01)

An Integrated Optogenetic and Bioelectronic Platform for Regulating Cardiomyocyte Function
by: Olurotimi A. Bolonduro, et al.
Published: (2024-09-01)

Spermidine reduces ISGylation and enhances ISG15–USP18 interaction
by: Haruka Etori, et al.
Published: (2025-05-01)

Exploring the relationship between circadian syndrome, serum uric acid levels, and hyperuricemia: evidence from NHANES 2005–2018
by: Haiyan Mao, et al.
Published: (2025-08-01)

Comprehensive analysis of the clinical and biological significances of polyamine metabolism in glioma
by: Fei Bai, et al.
Published: (2025-07-01)

Effect of preterm birth in rats on proliferation and hyperplasia of cardiomyocytes
by: V. V. Ivanova, et al.
Published: (2023-01-01)

Impact of hyperbilirubinemia on rat cardiomyocyte injury
by: Jiajia Zhao, et al.
Published: (2025-05-01)

Cell cycle arrest of cardiomyocytes in the context of cardiac regeneration
by: Qingling Xu, et al.
Published: (2025-04-01)

Cardiac endothelial cells and cardiomyocytes alter their communication properties in diabetic mice
by: Yan Wen, et al.
Published: (2025-04-01)

SNTA1-deficient human cardiomyocytes show shorter field potential duration and slower conduction velocity
by: Tao Dong, et al.
Published: (2025-08-01)

Brg1 and RUNX1 synergy in regulating TRPM4 channel in mouse cardiomyocytes
by: Tao Ban, et al.
Published: (2024-12-01)

RNA‐Binding Protein Hnrnpa1 Triggers Daughter Cardiomyocyte Formation by Promoting Cardiomyocyte Dedifferentiation and Cell Cycle Activity in a Post‐Transcriptional Manner
by: Chuling Li, et al.
Published: (2025-01-01)

Mitochondrial apoptosis in response to cardiac ischemia-reperfusion injury
by: Kaixin Wang, et al.
Published: (2025-01-01)

miRNA Expression: I/R Cardiomyocyte and Sevoflurane
by: José Luis Guerrero-Orriach, et al.
Published: (2024-12-01)

Respiration in isolated cardiomyocytes and microviscosity of their membranes in rats of different ages with heart failure
by: V. A. Korepanov, et al.
Published: (2023-04-01)