YAP/Nrf2 suppresses ferroptosis to alleviate acute lung injury induced by intestinal ischemia/reperfusion

YAP/Nrf2 suppresses ferroptosis to alleviate acute lung injury induced by intestinal ischemia/reperfusion

Intestinal ischemia reperfusion (II/R) injury is a common critical disease with high morbidity and mortality. The mechanism of II/R-induced acute lung injury (ALI) is not fully elucidated. Yes-associated protein (YAP), a downstream transcriptional coactivator of the Hippo signaling pathway, plays a...

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Bibliographic Details
Main Authors: Lu Tang, Chengjie Yang, Yanhua Peng, Mudi Liu, Na Wei, Xin Fan, Bo Yang, Jing Jia, Ye Chen, Jianguo Feng, Jun Zhou
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Redox Biology
Subjects:
Acute lung injury
Ferroptosis
Intestinal ischemia-reperfusion
Nrf2
YAP
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725003246
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