Iron-catalyzed aliphatic C–H functionalization to construct carbon–carbon bonds

Abstract Although cytochrome P450 enzymes are powerful catalysts for hydrogen-atom abstraction from alkanes by iron-oxo species, the process typically leads to oxygenated products due to ultrafast oxygen rebound. Developing synthetic catalysts that mimic this activity while avoiding oxygenation rema...

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Bibliographic Details
Main Authors: Lulu Zhou, Hengrui Cai, Dong Xie, Kangkang Sun, Shanmei Zhu, Mengying Guo, Wei Han
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60010-1
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