IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL
Experimental autoimmune encephalomyelitis in an adoptive transfer model is caused by injecting animal with activated T cells specific for a CNS antigen, e.g., basic myelin protein. Development of autimmune inflammation in such a model is connected with changed functional stateof encephalytogenic (EG...
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
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| Online Access: | https://www.mimmun.ru/mimmun/article/view/476 |
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| _version_ | 1849401462414639104 |
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| author | M. A. Nosov E. A. Korneva |
| author_facet | M. A. Nosov E. A. Korneva |
| author_sort | M. A. Nosov |
| collection | DOAJ |
| description | Experimental autoimmune encephalomyelitis in an adoptive transfer model is caused by injecting animal with activated T cells specific for a CNS antigen, e.g., basic myelin protein. Development of autimmune inflammation in such a model is connected with changed functional stateof encephalytogenic (EG) T cells in the coure of disease progression, as reflected by changes in their activation, proliferation and motility levels. Present work describes an original technique allowing for in vitro analysis of encephalytogenic T cell motility, and studying effects of certain compomemts of extracellular matrix upon migration and functional activities of EG T cells. |
| format | Article |
| id | doaj-art-2302584ecffc4e10b1bab6644e526f4c |
| institution | Kabale University |
| issn | 1563-0625 2313-741X |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj-art-2302584ecffc4e10b1bab6644e526f4c2025-08-20T03:37:46ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0112656556810.15789/1563-0625-2010-6-565-568473IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CELM. A. Nosov0E. A. Korneva1НИИ экспериментальной медицины СЗО РАМН, Санкт-Петербург Институт регенерационной медицины, Национальный Университет Ирландии, Голуэй, ИрландияНИИ экспериментальной медицины СЗО РАМН, Санкт-ПетербургExperimental autoimmune encephalomyelitis in an adoptive transfer model is caused by injecting animal with activated T cells specific for a CNS antigen, e.g., basic myelin protein. Development of autimmune inflammation in such a model is connected with changed functional stateof encephalytogenic (EG) T cells in the coure of disease progression, as reflected by changes in their activation, proliferation and motility levels. Present work describes an original technique allowing for in vitro analysis of encephalytogenic T cell motility, and studying effects of certain compomemts of extracellular matrix upon migration and functional activities of EG T cells.https://www.mimmun.ru/mimmun/article/view/476experimental autoimmune encephalomyelitisencephalytogenic t cellsmigrationextracellular matrix |
| spellingShingle | M. A. Nosov E. A. Korneva IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL Медицинская иммунология experimental autoimmune encephalomyelitis encephalytogenic t cells migration extracellular matrix |
| title | IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL |
| title_full | IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL |
| title_fullStr | IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL |
| title_full_unstemmed | IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL |
| title_short | IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL |
| title_sort | in vitro analysis of migration activity of encephalytogenic t cel |
| topic | experimental autoimmune encephalomyelitis encephalytogenic t cells migration extracellular matrix |
| url | https://www.mimmun.ru/mimmun/article/view/476 |
| work_keys_str_mv | AT manosov invitroanalysisofmigrationactivityofencephalytogenictcel AT eakorneva invitroanalysisofmigrationactivityofencephalytogenictcel |