MALIGNANT TUMORS OF BONES. MORBIDITY, MORTALITY, INDEX ACCURACY, SURVIVAL OF PATIENTS ACCORDING TO HISTOLOGICAL FORMS
Introduction. Standardized (world standard) incidence of malignant tumors of bones (S40,41) does not have has significant fluctuations. According to IARC among male population the most common incidence rates range from 1 to 2 cases per 100.000 and among female population – from 0.5 to 1.0 among wome...
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Russian Academy of Sciences, Tomsk National Research Medical Center
2016-02-01
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| Series: | Сибирский онкологический журнал |
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| Online Access: | https://www.siboncoj.ru/jour/article/view/178 |
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| author | V. M. Merabishvili O. F. Chepik E. N. Merabishvili |
| author_facet | V. M. Merabishvili O. F. Chepik E. N. Merabishvili |
| author_sort | V. M. Merabishvili |
| collection | DOAJ |
| description | Introduction. Standardized (world standard) incidence of malignant tumors of bones (S40,41) does not have has significant fluctuations. According to IARC among male population the most common incidence rates range from 1 to 2 cases per 100.000 and among female population – from 0.5 to 1.0 among women. Purpose of study. To study dynamics of morbidity and mortality from malignant tumors of bones, the quality of estimation, observed and relative survival of patients according to histological forms. The work of this level is held in Russia for the first time. Material and methods of study. There were used an open world and domestic sources to estimate the prevalence of malignant tumors of bones, databases of population-based cancer registers, classical methods of population-based estimation of the prevalence of malignant tumors of bones. results of study. The basis of this work is data from the Population-based Cancer Registry of St. Petersburg and special studies being held before its establishing in 1993. Annually in St. Petersburg there are registered 40–60 primary cases of malignant tumors of bones (S40, 41). The level of morphological verification of these malignancies in Russia is 82.1 %, in St. Petersburg – 84.9 %. There is a high rate of undefined stage: in Russia – 19.7 %, in St. Petersburg – 24.5 %, in Moscow – 23.5 %. During the first year of observation 27.3 % of patients die in Russia, 21.7 % in St. Petersburg, and 11.1 % in Moscow. In comparison with the average data (Eurocare program) the relative survival of patients in St. Petersburg is significantly lower: in men (St. Petersburg – 42.2–48.2 %, (Eurocare-3,4 – 55–58 %), in women (St. Petersburg – 32.2–54.6 % (Eurocare – 59–63 %). conclusion. Thus, in this work for the first time in Russia it is showed dynamics of absolute and relative incidence rates of malignant tumors of bones since 1980 by sex and age-specific indicators. It is presented a set of analytical indicators, the level of morphological verification, one-year mortality as well as observed and relative survival. For the first time it is provided dynamics of a 5-year survival of patients with malignant tumors of bone in accordance with the histological forms. There is marked a growth of a 5-year survival rates of patients with chondrosarcoma and osteosarcoma. |
| format | Article |
| id | doaj-art-22f80f7b1eff48b28fad0c5da889f646 |
| institution | Kabale University |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| publishDate | 2016-02-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj-art-22f80f7b1eff48b28fad0c5da889f6462025-08-20T03:56:24ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682016-02-01131319178MALIGNANT TUMORS OF BONES. MORBIDITY, MORTALITY, INDEX ACCURACY, SURVIVAL OF PATIENTS ACCORDING TO HISTOLOGICAL FORMSV. M. Merabishvili0O. F. Chepik1E. N. Merabishvili2N.N. Petrov Research Institute of Oncology, St. PetersburgN.N. Petrov Research Institute of Oncology, St. PetersburgNorthwestern State Medical University named after I.I. Mechnikov, St. PetersburgIntroduction. Standardized (world standard) incidence of malignant tumors of bones (S40,41) does not have has significant fluctuations. According to IARC among male population the most common incidence rates range from 1 to 2 cases per 100.000 and among female population – from 0.5 to 1.0 among women. Purpose of study. To study dynamics of morbidity and mortality from malignant tumors of bones, the quality of estimation, observed and relative survival of patients according to histological forms. The work of this level is held in Russia for the first time. Material and methods of study. There were used an open world and domestic sources to estimate the prevalence of malignant tumors of bones, databases of population-based cancer registers, classical methods of population-based estimation of the prevalence of malignant tumors of bones. results of study. The basis of this work is data from the Population-based Cancer Registry of St. Petersburg and special studies being held before its establishing in 1993. Annually in St. Petersburg there are registered 40–60 primary cases of malignant tumors of bones (S40, 41). The level of morphological verification of these malignancies in Russia is 82.1 %, in St. Petersburg – 84.9 %. There is a high rate of undefined stage: in Russia – 19.7 %, in St. Petersburg – 24.5 %, in Moscow – 23.5 %. During the first year of observation 27.3 % of patients die in Russia, 21.7 % in St. Petersburg, and 11.1 % in Moscow. In comparison with the average data (Eurocare program) the relative survival of patients in St. Petersburg is significantly lower: in men (St. Petersburg – 42.2–48.2 %, (Eurocare-3,4 – 55–58 %), in women (St. Petersburg – 32.2–54.6 % (Eurocare – 59–63 %). conclusion. Thus, in this work for the first time in Russia it is showed dynamics of absolute and relative incidence rates of malignant tumors of bones since 1980 by sex and age-specific indicators. It is presented a set of analytical indicators, the level of morphological verification, one-year mortality as well as observed and relative survival. For the first time it is provided dynamics of a 5-year survival of patients with malignant tumors of bone in accordance with the histological forms. There is marked a growth of a 5-year survival rates of patients with chondrosarcoma and osteosarcoma.https://www.siboncoj.ru/jour/article/view/178malignant tumors of bonesincidencemortalityindex accuracysurvivalhistology |
| spellingShingle | V. M. Merabishvili O. F. Chepik E. N. Merabishvili MALIGNANT TUMORS OF BONES. MORBIDITY, MORTALITY, INDEX ACCURACY, SURVIVAL OF PATIENTS ACCORDING TO HISTOLOGICAL FORMS Сибирский онкологический журнал malignant tumors of bones incidence mortality index accuracy survival histology |
| title | MALIGNANT TUMORS OF BONES. MORBIDITY, MORTALITY, INDEX ACCURACY, SURVIVAL OF PATIENTS ACCORDING TO HISTOLOGICAL FORMS |
| title_full | MALIGNANT TUMORS OF BONES. MORBIDITY, MORTALITY, INDEX ACCURACY, SURVIVAL OF PATIENTS ACCORDING TO HISTOLOGICAL FORMS |
| title_fullStr | MALIGNANT TUMORS OF BONES. MORBIDITY, MORTALITY, INDEX ACCURACY, SURVIVAL OF PATIENTS ACCORDING TO HISTOLOGICAL FORMS |
| title_full_unstemmed | MALIGNANT TUMORS OF BONES. MORBIDITY, MORTALITY, INDEX ACCURACY, SURVIVAL OF PATIENTS ACCORDING TO HISTOLOGICAL FORMS |
| title_short | MALIGNANT TUMORS OF BONES. MORBIDITY, MORTALITY, INDEX ACCURACY, SURVIVAL OF PATIENTS ACCORDING TO HISTOLOGICAL FORMS |
| title_sort | malignant tumors of bones morbidity mortality index accuracy survival of patients according to histological forms |
| topic | malignant tumors of bones incidence mortality index accuracy survival histology |
| url | https://www.siboncoj.ru/jour/article/view/178 |
| work_keys_str_mv | AT vmmerabishvili malignanttumorsofbonesmorbiditymortalityindexaccuracysurvivalofpatientsaccordingtohistologicalforms AT ofchepik malignanttumorsofbonesmorbiditymortalityindexaccuracysurvivalofpatientsaccordingtohistologicalforms AT enmerabishvili malignanttumorsofbonesmorbiditymortalityindexaccuracysurvivalofpatientsaccordingtohistologicalforms |