Hyperglycemic effect of n- methylglucamine antimonite (glucantime) in mice
N- methylglucamine antimonite (Glucantime) was injected intramuscularly to ten albino mice iri a dose of 15- 30 mg/kg for the first three days and then 60 mg/kg for twelve days. Glucantime was also injected in the same manner but in double doses to another teri mice. No drug was administred to ten m...
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| Format: | Article |
| Language: | English |
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=899 |
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| author | Murat YURDAKÖK Erol KINIK Serdar DİKER Hüdaverdi ERER Uğur DİLMEN Mehmet. CEYHAN Osman KUTSAL |
| author_facet | Murat YURDAKÖK Erol KINIK Serdar DİKER Hüdaverdi ERER Uğur DİLMEN Mehmet. CEYHAN Osman KUTSAL |
| author_sort | Murat YURDAKÖK |
| collection | DOAJ |
| description | N- methylglucamine antimonite (Glucantime) was injected
intramuscularly to ten albino mice iri a dose of 15- 30 mg/kg for
the first three days and then 60 mg/kg for twelve days. Glucantime was
also injected in the same manner but in double doses to another teri mice.
No drug was administred to ten mice that were used as a control group.
In the sixteenth day, there were hyperglyce~ia, parenchymatous and
vacuolar degeneration, hepatocellular necrosis and inflammation in the
livers of the experimental mice which were marked asa double dose group.
The frequent monitoring of blood glucose of the patie:nts with Kala-azar
receiving Glucantime was suggested. |
| format | Article |
| id | doaj-art-22f0c3e5d9df4a6e8c7994fb0b2b2209 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-22f0c3e5d9df4a6e8c7994fb0b2b22092025-01-03T01:36:54ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-1953116569899Hyperglycemic effect of n- methylglucamine antimonite (glucantime) in miceMurat YURDAKÖK0Erol KINIK1Serdar DİKER2Hüdaverdi ERER3Uğur DİLMEN4Mehmet. CEYHAN5Osman KUTSAL6H. Ü. Halk Sağlığı Enstitüsü, Ankara, TürkiyeH. Ü. Tıp Fakü1tesi Pediatri Anabilim Dalı, Ankara, TürkiyeA. Ü. Veteriner Fakültesi Mikrobiyoloji Anabilim Dalı, Ankara, TürkiyeS. Ü. Veteriner Fakültesi Patoloji Anabilim Dalı, Konya, TürkiyeTürkiye Sağlık ve Tedavi Vakfı Ahmet Örs Hastanesi, Ankara, TürkiyeH. Ü. Tıp Fakültesi Pediatri Anabilim Dalı, Ankara, TürkiyeA. Ü. Veteriner Fakültesi Patoloji Anabilim Dalı, Ankara, TürkiyeN- methylglucamine antimonite (Glucantime) was injected intramuscularly to ten albino mice iri a dose of 15- 30 mg/kg for the first three days and then 60 mg/kg for twelve days. Glucantime was also injected in the same manner but in double doses to another teri mice. No drug was administred to ten mice that were used as a control group. In the sixteenth day, there were hyperglyce~ia, parenchymatous and vacuolar degeneration, hepatocellular necrosis and inflammation in the livers of the experimental mice which were marked asa double dose group. The frequent monitoring of blood glucose of the patie:nts with Kala-azar receiving Glucantime was suggested.http://eurasianjvetsci.org/pdf.php3?id=899 |
| spellingShingle | Murat YURDAKÖK Erol KINIK Serdar DİKER Hüdaverdi ERER Uğur DİLMEN Mehmet. CEYHAN Osman KUTSAL Hyperglycemic effect of n- methylglucamine antimonite (glucantime) in mice Eurasian Journal of Veterinary Sciences |
| title | Hyperglycemic effect of n- methylglucamine antimonite (glucantime) in mice |
| title_full | Hyperglycemic effect of n- methylglucamine antimonite (glucantime) in mice |
| title_fullStr | Hyperglycemic effect of n- methylglucamine antimonite (glucantime) in mice |
| title_full_unstemmed | Hyperglycemic effect of n- methylglucamine antimonite (glucantime) in mice |
| title_short | Hyperglycemic effect of n- methylglucamine antimonite (glucantime) in mice |
| title_sort | hyperglycemic effect of n methylglucamine antimonite glucantime in mice |
| url | http://eurasianjvetsci.org/pdf.php3?id=899 |
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