Securing the Future: Strategies for Global Polio Vaccine Security Amid Eradication Efforts
<b>Background/Objectives:</b> As we commemorate 50 years of the Expanded Programme on Immunization (EPI), the global mission to eradicate polio stands at a critical juncture. While remarkable progress has been made over the past decades, ensuring a steady supply of polio vaccines remains...
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| Format: | Article |
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MDPI AG
2024-12-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/12/12/1369 |
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| author | Vachagan Harutyunyan Ann Ottosen Rachel M. Burke Derek Ehrhardt Meredith Shirey Rissa Durham David Woods |
| author_facet | Vachagan Harutyunyan Ann Ottosen Rachel M. Burke Derek Ehrhardt Meredith Shirey Rissa Durham David Woods |
| author_sort | Vachagan Harutyunyan |
| collection | DOAJ |
| description | <b>Background/Objectives:</b> As we commemorate 50 years of the Expanded Programme on Immunization (EPI), the global mission to eradicate polio stands at a critical juncture. While remarkable progress has been made over the past decades, ensuring a steady supply of polio vaccines remains a significant challenge that could undermine these achievements. This manuscript aims to address the complexities of polio vaccine security within the context of the Immunization Agenda 2030 (IA2030) and the Global Polio Eradication Strategy 2022–2029, proposing actionable strategies to strengthen the vaccine supply. <b>Methods:</b> This manuscript analyzes obstacles to vaccine security, including supply disruptions and market uncertainties. It presents the Polio Vaccine Security Framework as a key strategy for addressing these challenges. Data were gathered from Global Polio Eradication Initiative (GPEI) reports, consultations with key stakeholders, and analyses of past vaccine shortages. <b>Results:</b> The findings indicate that the primary risks to vaccine security include the lack of a coherent long-term policy framework on polio vaccination, the absence of a clear polio vaccine development roadmap, and insufficient long-term, predictable forecasting. Additionally, stronger coordination is needed between stakeholders involved in vaccine supply, polio containment, and research, as well as addressing challenges related to financing and access to resources. <b>Conclusions:</b> A robust, adaptable, and sustainable approach to vaccine security, proposed in the Polio Vaccine Security Framework, is critical to achieving and sustaining polio eradication. Collaboration among policymakers, manufacturers, and stakeholders to implement it is essential to ensure the uninterrupted supply of polio vaccines, protecting the progress made over the past half century, and preventing a resurgence of poliovirus in the future. |
| format | Article |
| id | doaj-art-22ebb503534c46a0a7a238d04748af98 |
| institution | DOAJ |
| issn | 2076-393X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj-art-22ebb503534c46a0a7a238d04748af982025-08-20T02:50:44ZengMDPI AGVaccines2076-393X2024-12-011212136910.3390/vaccines12121369Securing the Future: Strategies for Global Polio Vaccine Security Amid Eradication EffortsVachagan Harutyunyan0Ann Ottosen1Rachel M. Burke2Derek Ehrhardt3Meredith Shirey4Rissa Durham5David Woods6World Health Organization, 1211 Geneva, SwitzerlandUNICEF, 2150 Copenhagen, DenmarkGates Foundation, Seattle, WA 98109, USAWorld Health Organization, 1211 Geneva, SwitzerlandIndependent ResearcherGates Foundation, Seattle, WA 98109, USAWorld Health Organization, 1211 Geneva, Switzerland<b>Background/Objectives:</b> As we commemorate 50 years of the Expanded Programme on Immunization (EPI), the global mission to eradicate polio stands at a critical juncture. While remarkable progress has been made over the past decades, ensuring a steady supply of polio vaccines remains a significant challenge that could undermine these achievements. This manuscript aims to address the complexities of polio vaccine security within the context of the Immunization Agenda 2030 (IA2030) and the Global Polio Eradication Strategy 2022–2029, proposing actionable strategies to strengthen the vaccine supply. <b>Methods:</b> This manuscript analyzes obstacles to vaccine security, including supply disruptions and market uncertainties. It presents the Polio Vaccine Security Framework as a key strategy for addressing these challenges. Data were gathered from Global Polio Eradication Initiative (GPEI) reports, consultations with key stakeholders, and analyses of past vaccine shortages. <b>Results:</b> The findings indicate that the primary risks to vaccine security include the lack of a coherent long-term policy framework on polio vaccination, the absence of a clear polio vaccine development roadmap, and insufficient long-term, predictable forecasting. Additionally, stronger coordination is needed between stakeholders involved in vaccine supply, polio containment, and research, as well as addressing challenges related to financing and access to resources. <b>Conclusions:</b> A robust, adaptable, and sustainable approach to vaccine security, proposed in the Polio Vaccine Security Framework, is critical to achieving and sustaining polio eradication. Collaboration among policymakers, manufacturers, and stakeholders to implement it is essential to ensure the uninterrupted supply of polio vaccines, protecting the progress made over the past half century, and preventing a resurgence of poliovirus in the future.https://www.mdpi.com/2076-393X/12/12/1369polio eradicationvaccine securityglobal OPV stockpileimmunization policyinactivated poliovirus vaccine (IPV)oral poliovirus vaccine (OPV) |
| spellingShingle | Vachagan Harutyunyan Ann Ottosen Rachel M. Burke Derek Ehrhardt Meredith Shirey Rissa Durham David Woods Securing the Future: Strategies for Global Polio Vaccine Security Amid Eradication Efforts Vaccines polio eradication vaccine security global OPV stockpile immunization policy inactivated poliovirus vaccine (IPV) oral poliovirus vaccine (OPV) |
| title | Securing the Future: Strategies for Global Polio Vaccine Security Amid Eradication Efforts |
| title_full | Securing the Future: Strategies for Global Polio Vaccine Security Amid Eradication Efforts |
| title_fullStr | Securing the Future: Strategies for Global Polio Vaccine Security Amid Eradication Efforts |
| title_full_unstemmed | Securing the Future: Strategies for Global Polio Vaccine Security Amid Eradication Efforts |
| title_short | Securing the Future: Strategies for Global Polio Vaccine Security Amid Eradication Efforts |
| title_sort | securing the future strategies for global polio vaccine security amid eradication efforts |
| topic | polio eradication vaccine security global OPV stockpile immunization policy inactivated poliovirus vaccine (IPV) oral poliovirus vaccine (OPV) |
| url | https://www.mdpi.com/2076-393X/12/12/1369 |
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