An analysis of gene expression profiles through machine learning uncovers the new diagnostic signature for diabetic foot ulcers

An analysis of gene expression profiles through machine learning uncovers the new diagnostic signature for diabetic foot ulcers

PurposeDiabetic foot ulcers (DFUs), a serious diabetes complication, greatly increase disability and mortality, underscoring the need for effective diagnostic markers.MethodsWe used GSE199939 and GSE134431 datasets from the Gene Expression Omnibus (GEO) database, removed batch effects, and identifie...

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Bibliographic Details
Main Authors: Yingnan Li, Ning Xiao, Zhuoqun Wang, Wenhai Wang, Fengjiao Li, Jiren Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Genetics
Subjects:
diabetic foot ulcers
WGCNA
PPI network
melanin synthesis
diagnosis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1620749/full
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