Impact of phytochemical-based hydrocolloid dressings on wound healing: A comparative review

Background: Wound healing is an important occurrence consisting of a myriad biochemical processes. The recent introduction of phytochemical-based dressings to expedite wound healing uses a multi-targeted approach including antimicrobial, anti-inflammatory and antioxidant activity. Aim: The review a...

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Bibliographic Details
Main Authors: Sipho Sibanda, Mapula Razwinani, Keolebogile Shirley Motaung
Format: Article
Language:English
Published: AOSIS 2025-01-01
Series:Journal of Medicinal Plants for Economic Development
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Online Access:https://jomped.org/index.php/jomped/article/view/267
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Summary:Background: Wound healing is an important occurrence consisting of a myriad biochemical processes. The recent introduction of phytochemical-based dressings to expedite wound healing uses a multi-targeted approach including antimicrobial, anti-inflammatory and antioxidant activity. Aim: The review aimed to conduct an exhaustive search of the existing literature on plant-based hydrocolloid dressings for wound healing and to evaluate the dressing efficacy in comparison to standard dressings. Setting: The review offers a worldwide overview of plant-based hydrocolloid dressings and their use. Methods: A systematic search using keywords was done to identify clinical and randomised control trials from 2019 to 2024. The following databases were queried: Cochrane Library, Embase, PubMed, Scopus, Science Direct and Web of Science. Data appraisal was done by an analysis of the data quality by the authors. Results: Of a total of 866 records identified, 4 qualified for further assessment. The data retrieved showed that the use of phytochemical-based hydrocolloids is more effective compared to non-plant-based hydrocolloids. Conclusion: The data analysis revealed that there are few research studies on plant-based hydrocolloids, and there is a need for further research in the area. In addition, the dressings significantly expedite wound healing offering a multifaceted approach because of the different mechanisms of action including antioxidant, anti-inflammatory and cell proliferation. Contribution: This study highlights the need for further studies on hydrocolloids produced from plant extracts for effective wound healing.
ISSN:2519-559X
2616-4809