Exploring the role of NLRP3 infalmmasome in diabetes: a literature review and bibliometric analysis
BackgroundDiabetes has emerged as the foremost public health challenge of the 21st century, with a notable shift towards managing it through an inflammatory lens. This study seeks to investigate the role of NLRP3 infalmmasome in diabetes over the past ten years, leveraging bibliometric analysis to p...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-12-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2024.1443798/full |
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| author | Yi Tan Shaotao Chen Tianjiao Gao Sixian Wang Xinfeng Zhou Mingjun Liu |
| author_facet | Yi Tan Shaotao Chen Tianjiao Gao Sixian Wang Xinfeng Zhou Mingjun Liu |
| author_sort | Yi Tan |
| collection | DOAJ |
| description | BackgroundDiabetes has emerged as the foremost public health challenge of the 21st century, with a notable shift towards managing it through an inflammatory lens. This study seeks to investigate the role of NLRP3 infalmmasome in diabetes over the past ten years, leveraging bibliometric analysis to pinpoint prevailing trends, underscore critical focal points, and establish a roadmap for subsequent research endeavors.MethodA literature search was conducted based on the SCI-E database, and all recorded results were downloaded in plain text format for subsequent analysis. The analysis was carried out using Vosviewer1.6.18, citespace6.3R1, and Microsoft Excel 2021 software, focusing on the following terms: country, institution, author, journal, references, and keywords.ResultsFrom January 1, 2014, to December 31, 2023, a total of 1373 articles were retrieved, with China, the United States, and Italy contributing the majority of records. Harbin Medical University, Nanjing Medical University, and Central South University stand as the top three most productive institutions. “International Journal of Molecular Sciences” leads the way with the highest number of publications, closely followed by “Frontiers in Immunology” and “Frontiers in Pharmacology.” Authors Wang Wei boast the most publications, closely followed by Li Xiang and Wang Yan. Within the superimposed keyword network, four primary clusters emerge: (1) exploring the link between NLRP3 infalmmasome and inflammatory diseases like diabetes; (2) investigating the cellular-level pathogenesis of diabetes-related conditions; (3) examining diabetes characteristics and associated suppression techniques; (4) studying cell morphology alterations, including pyroptosis. Over the past five years, key topics in this field have revolved around the “heart”, “damage”, “caspase 1 activation”, “NLRP3”, and “diabetic kidney disease”.ConclusionThis paper has identified the hot spots and trends concerning the role of NLRP3 infalmmasome in diabetes, thereby providing a valuable reference for future research. Furthermore, it is anticipated that pyroptosis and diabetes-related diseases will become frontier research topics that may garner significant attention in the coming years. |
| format | Article |
| id | doaj-art-22e01782038e4820bec1bb3c9b2193fc |
| institution | Kabale University |
| issn | 1664-2392 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj-art-22e01782038e4820bec1bb3c9b2193fc2024-12-09T04:24:41ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922024-12-011510.3389/fendo.2024.14437981443798Exploring the role of NLRP3 infalmmasome in diabetes: a literature review and bibliometric analysisYi Tan0Shaotao Chen1Tianjiao Gao2Sixian Wang3Xinfeng Zhou4Mingjun Liu5Departments of Acupuncture and Massage, Changchun University of Chinese Medicine, Changchun, Jilin, ChinaDepartments of Acupuncture and Massage, Changchun University of Chinese Medicine, Changchun, Jilin, ChinaOffice of Scientific Research, Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, ChinaDepartments of Acupuncture and Massage, Changchun University of Chinese Medicine, Changchun, Jilin, ChinaDepartments of Acupuncture and Massage, Changchun University of Chinese Medicine, Changchun, Jilin, ChinaDepartments of Acupuncture and Massage, Changchun University of Chinese Medicine, Changchun, Jilin, ChinaBackgroundDiabetes has emerged as the foremost public health challenge of the 21st century, with a notable shift towards managing it through an inflammatory lens. This study seeks to investigate the role of NLRP3 infalmmasome in diabetes over the past ten years, leveraging bibliometric analysis to pinpoint prevailing trends, underscore critical focal points, and establish a roadmap for subsequent research endeavors.MethodA literature search was conducted based on the SCI-E database, and all recorded results were downloaded in plain text format for subsequent analysis. The analysis was carried out using Vosviewer1.6.18, citespace6.3R1, and Microsoft Excel 2021 software, focusing on the following terms: country, institution, author, journal, references, and keywords.ResultsFrom January 1, 2014, to December 31, 2023, a total of 1373 articles were retrieved, with China, the United States, and Italy contributing the majority of records. Harbin Medical University, Nanjing Medical University, and Central South University stand as the top three most productive institutions. “International Journal of Molecular Sciences” leads the way with the highest number of publications, closely followed by “Frontiers in Immunology” and “Frontiers in Pharmacology.” Authors Wang Wei boast the most publications, closely followed by Li Xiang and Wang Yan. Within the superimposed keyword network, four primary clusters emerge: (1) exploring the link between NLRP3 infalmmasome and inflammatory diseases like diabetes; (2) investigating the cellular-level pathogenesis of diabetes-related conditions; (3) examining diabetes characteristics and associated suppression techniques; (4) studying cell morphology alterations, including pyroptosis. Over the past five years, key topics in this field have revolved around the “heart”, “damage”, “caspase 1 activation”, “NLRP3”, and “diabetic kidney disease”.ConclusionThis paper has identified the hot spots and trends concerning the role of NLRP3 infalmmasome in diabetes, thereby providing a valuable reference for future research. Furthermore, it is anticipated that pyroptosis and diabetes-related diseases will become frontier research topics that may garner significant attention in the coming years.https://www.frontiersin.org/articles/10.3389/fendo.2024.1443798/fullNLRP3 infalmmasomediabetesbibliometric analysisVOSviewerCitespace |
| spellingShingle | Yi Tan Shaotao Chen Tianjiao Gao Sixian Wang Xinfeng Zhou Mingjun Liu Exploring the role of NLRP3 infalmmasome in diabetes: a literature review and bibliometric analysis Frontiers in Endocrinology NLRP3 infalmmasome diabetes bibliometric analysis VOSviewer Citespace |
| title | Exploring the role of NLRP3 infalmmasome in diabetes: a literature review and bibliometric analysis |
| title_full | Exploring the role of NLRP3 infalmmasome in diabetes: a literature review and bibliometric analysis |
| title_fullStr | Exploring the role of NLRP3 infalmmasome in diabetes: a literature review and bibliometric analysis |
| title_full_unstemmed | Exploring the role of NLRP3 infalmmasome in diabetes: a literature review and bibliometric analysis |
| title_short | Exploring the role of NLRP3 infalmmasome in diabetes: a literature review and bibliometric analysis |
| title_sort | exploring the role of nlrp3 infalmmasome in diabetes a literature review and bibliometric analysis |
| topic | NLRP3 infalmmasome diabetes bibliometric analysis VOSviewer Citespace |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2024.1443798/full |
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