Role of Educational Level in Kidney Transplant Outcomes

<b>Background</b>: Kidney transplantation outcomes are correlated to many factors, including the socioeconomics conditions and the educational level. <b>Methods</b>: We evaluated the role of educational level on patient and graft survival in a population of 456 kidney transpl...

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Main Authors: Francesco Leonforte, Pierfrancesco Veroux, Antonio Mistretta, Alessia Giaquinta, Martina Maria Giambra, Domenico Zerbo, Giuseppe Roscitano, Concetta De Pasquale, Maria Luisa Pistorio, Antonio D’Anna, Carmelo Cusmano, Roberta Granata, Giordana Riccioli, Marianna Scribano, Massimiliano Veroux
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomedicines
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Online Access:https://www.mdpi.com/2227-9059/13/4/916
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author Francesco Leonforte
Pierfrancesco Veroux
Antonio Mistretta
Alessia Giaquinta
Martina Maria Giambra
Domenico Zerbo
Giuseppe Roscitano
Concetta De Pasquale
Maria Luisa Pistorio
Antonio D’Anna
Carmelo Cusmano
Roberta Granata
Giordana Riccioli
Marianna Scribano
Massimiliano Veroux
author_facet Francesco Leonforte
Pierfrancesco Veroux
Antonio Mistretta
Alessia Giaquinta
Martina Maria Giambra
Domenico Zerbo
Giuseppe Roscitano
Concetta De Pasquale
Maria Luisa Pistorio
Antonio D’Anna
Carmelo Cusmano
Roberta Granata
Giordana Riccioli
Marianna Scribano
Massimiliano Veroux
author_sort Francesco Leonforte
collection DOAJ
description <b>Background</b>: Kidney transplantation outcomes are correlated to many factors, including the socioeconomics conditions and the educational level. <b>Methods</b>: We evaluated the role of educational level on patient and graft survival in a population of 456 kidney transplant recipients. Patients were divided into two groups on the basis of their pre-transplant educational status: patients with primary education (elementary or middle school, as low education) were compared with patients with a secondary school education (high school or a university degree, as high education). <b>Results</b>: Among the 456 patients considered for this analysis, 161 patients had a low educational status, and 295 had a high educational status. Patients with a low educational status were more rarely employed (66.1% vs. 32.5%, <i>p</i> < 0.001), with a high rate of retired patients compared to high-educational status patients (35.6% vs. 10.6%, <i>p</i> < 0.001). Although the educational status did not influence the graft function, the 1-year (88.1% vs. 96.2%, <i>p</i> = 0.0008), 5-year (77.6% vs. 88.8%, <i>p</i> = 0.001), and 10-year (62.1% vs. 75%, <i>p</i> = 0.003) graft survival rates were significantly lower in patients with low educational status compared with high-educational status patients, respectively. Patient survival at 1-year (94.4% vs. 97.6%, <i>p</i> = 0.073), 5-year (85% vs. 92.5%, <i>p</i> = 0.011), and 10-year (75.7% vs. 83.4%, <i>p</i> = 0.042) follow-up was significantly lower in patients with low educational status. <b>Conclusions</b>: Low socioeconomic conditions and educational level had a negative impact on kidney transplant outcomes. Improving access to education and providing targeted educational support and health literacy could enhance treatment adherence and reduce disparities in transplant outcomes.
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spelling doaj-art-22dcb7833a4e4b7c92876612b0e2c0ce2025-08-20T02:24:39ZengMDPI AGBiomedicines2227-90592025-04-0113491610.3390/biomedicines13040916Role of Educational Level in Kidney Transplant OutcomesFrancesco Leonforte0Pierfrancesco Veroux1Antonio Mistretta2Alessia Giaquinta3Martina Maria Giambra4Domenico Zerbo5Giuseppe Roscitano6Concetta De Pasquale7Maria Luisa Pistorio8Antonio D’Anna9Carmelo Cusmano10Roberta Granata11Giordana Riccioli12Marianna Scribano13Massimiliano Veroux14Public Health Physician, University Hospital Polyclinic “G. Rodolico San Marco”,95124 Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies, University of Catania, 95124 Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies, University of Catania, 95124 Catania, ItalyVascular Surgery and Organ Transplant Unit, University Hospital of Catania, 95121 Catania, ItalyVascular Surgery and Organ Transplant Unit, University Hospital of Catania, 95121 Catania, ItalyVascular Surgery and Organ Transplant Unit, University Hospital of Catania, 95121 Catania, ItalyVascular Surgery and Organ Transplant Unit, University Hospital of Catania, 95121 Catania, ItalyVascular Surgery and Organ Transplant Unit, University Hospital of Catania, 95121 Catania, ItalyVascular Surgery and Organ Transplant Unit, University Hospital of Catania, 95121 Catania, ItalyPublic Health Physician, University Hospital Polyclinic “G. Rodolico San Marco”,95124 Catania, ItalyPublic Health Physician, University Hospital Polyclinic “G. Rodolico San Marco”,95124 Catania, ItalyGeneral Surgery Unit, Azienda Policlinico San Marco, University of Catania, 95124 Catania, ItalyGeneral Surgery Unit, Azienda Policlinico San Marco, University of Catania, 95124 Catania, ItalyGeneral Surgery Unit, Azienda Policlinico San Marco, University of Catania, 95124 Catania, ItalyVascular Surgery and Organ Transplant Unit, University Hospital of Catania, 95121 Catania, Italy<b>Background</b>: Kidney transplantation outcomes are correlated to many factors, including the socioeconomics conditions and the educational level. <b>Methods</b>: We evaluated the role of educational level on patient and graft survival in a population of 456 kidney transplant recipients. Patients were divided into two groups on the basis of their pre-transplant educational status: patients with primary education (elementary or middle school, as low education) were compared with patients with a secondary school education (high school or a university degree, as high education). <b>Results</b>: Among the 456 patients considered for this analysis, 161 patients had a low educational status, and 295 had a high educational status. Patients with a low educational status were more rarely employed (66.1% vs. 32.5%, <i>p</i> < 0.001), with a high rate of retired patients compared to high-educational status patients (35.6% vs. 10.6%, <i>p</i> < 0.001). Although the educational status did not influence the graft function, the 1-year (88.1% vs. 96.2%, <i>p</i> = 0.0008), 5-year (77.6% vs. 88.8%, <i>p</i> = 0.001), and 10-year (62.1% vs. 75%, <i>p</i> = 0.003) graft survival rates were significantly lower in patients with low educational status compared with high-educational status patients, respectively. Patient survival at 1-year (94.4% vs. 97.6%, <i>p</i> = 0.073), 5-year (85% vs. 92.5%, <i>p</i> = 0.011), and 10-year (75.7% vs. 83.4%, <i>p</i> = 0.042) follow-up was significantly lower in patients with low educational status. <b>Conclusions</b>: Low socioeconomic conditions and educational level had a negative impact on kidney transplant outcomes. Improving access to education and providing targeted educational support and health literacy could enhance treatment adherence and reduce disparities in transplant outcomes.https://www.mdpi.com/2227-9059/13/4/916kidney transplantationliving donordeceased donorgraft survivalpatient survivalemployment
spellingShingle Francesco Leonforte
Pierfrancesco Veroux
Antonio Mistretta
Alessia Giaquinta
Martina Maria Giambra
Domenico Zerbo
Giuseppe Roscitano
Concetta De Pasquale
Maria Luisa Pistorio
Antonio D’Anna
Carmelo Cusmano
Roberta Granata
Giordana Riccioli
Marianna Scribano
Massimiliano Veroux
Role of Educational Level in Kidney Transplant Outcomes
Biomedicines
kidney transplantation
living donor
deceased donor
graft survival
patient survival
employment
title Role of Educational Level in Kidney Transplant Outcomes
title_full Role of Educational Level in Kidney Transplant Outcomes
title_fullStr Role of Educational Level in Kidney Transplant Outcomes
title_full_unstemmed Role of Educational Level in Kidney Transplant Outcomes
title_short Role of Educational Level in Kidney Transplant Outcomes
title_sort role of educational level in kidney transplant outcomes
topic kidney transplantation
living donor
deceased donor
graft survival
patient survival
employment
url https://www.mdpi.com/2227-9059/13/4/916
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