Determinants of antiretroviral therapy adherence among transgender women in South Africa

Background: Transgender women bear a huge burden of human immunodeficiency virus (HIV) in South Africa. However, they are not fully engaged in healthcare across the HIV continuum of care. In addition, transgender women face multiple facets of stigma and discrimination as well as socio-economic inequ...

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Main Authors: Leonashia Leigh-Ann van der Merwe, Idah Moyo, Azwihangwisi H. Mavhandu-Mudzusi
Format: Article
Language:English
Published: AOSIS 2024-04-01
Series:South African Family Practice
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Online Access:https://safpj.co.za/index.php/safpj/article/view/5869
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author Leonashia Leigh-Ann van der Merwe
Idah Moyo
Azwihangwisi H. Mavhandu-Mudzusi
author_facet Leonashia Leigh-Ann van der Merwe
Idah Moyo
Azwihangwisi H. Mavhandu-Mudzusi
author_sort Leonashia Leigh-Ann van der Merwe
collection DOAJ
description Background: Transgender women bear a huge burden of human immunodeficiency virus (HIV) in South Africa. However, they are not fully engaged in healthcare across the HIV continuum of care. In addition, transgender women face multiple facets of stigma and discrimination as well as socio-economic inequalities, which all have a negative impact on antiretroviral therapy (ART) adherence. Objective: The study aimed at exploring and describing the experiences of ART adherence of transgender women living with HIV in the Buffalo City Metro Municipality. Methods: The study employed an interpretative phenomenological analysis (IPA) design. Twelve participants were enrolled using a snowballing sampling technique. Data were collected using semi-structured interviews and analysed using an IPA framework. Results: While exploring determinants to ART adherence among transgender women living with HIV in Buffalo City Metro, two superordinate themes emerged: enablers to ART adherence and psychosocial factors promoting adherence. The study found that factors such as differentiated ART service delivery, ARV medicines-related factors, motivators for taking treatment and support systems facilitated ART adherence. Conclusion: Emerging from this study is the need to scale up differentiated, person-centred ART service deliveries that will enhance access and adherence to treatment for transgender women. Contribution: This study provides unique insights on factors enhancing ART adherence among transgender women. There is a paucity of literature on access to HIV care services for key and vulnerable populations, and these findings will be shared in the country and in the region.
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institution Kabale University
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spelling doaj-art-22dbc6d3442a4d178bed467df4a19a692025-08-20T04:03:12ZengAOSISSouth African Family Practice2078-61902078-62042024-04-01661e1e810.4102/safp.v66i1.58694416Determinants of antiretroviral therapy adherence among transgender women in South AfricaLeonashia Leigh-Ann van der Merwe0Idah Moyo1Azwihangwisi H. Mavhandu-Mudzusi2Department of Health Studies, College of Human Sciences, University of South Africa, PretoriaDepartment of Health Studies, College of Human Sciences, University of South Africa, Pretoria, South Africa; and Department of HIV Services, Population Solutions for Health, HarareSchool of Social Sciences, College of Human Sciences, University of South Africa, PretoriaBackground: Transgender women bear a huge burden of human immunodeficiency virus (HIV) in South Africa. However, they are not fully engaged in healthcare across the HIV continuum of care. In addition, transgender women face multiple facets of stigma and discrimination as well as socio-economic inequalities, which all have a negative impact on antiretroviral therapy (ART) adherence. Objective: The study aimed at exploring and describing the experiences of ART adherence of transgender women living with HIV in the Buffalo City Metro Municipality. Methods: The study employed an interpretative phenomenological analysis (IPA) design. Twelve participants were enrolled using a snowballing sampling technique. Data were collected using semi-structured interviews and analysed using an IPA framework. Results: While exploring determinants to ART adherence among transgender women living with HIV in Buffalo City Metro, two superordinate themes emerged: enablers to ART adherence and psychosocial factors promoting adherence. The study found that factors such as differentiated ART service delivery, ARV medicines-related factors, motivators for taking treatment and support systems facilitated ART adherence. Conclusion: Emerging from this study is the need to scale up differentiated, person-centred ART service deliveries that will enhance access and adherence to treatment for transgender women. Contribution: This study provides unique insights on factors enhancing ART adherence among transgender women. There is a paucity of literature on access to HIV care services for key and vulnerable populations, and these findings will be shared in the country and in the region.https://safpj.co.za/index.php/safpj/article/view/5869art adherencedeterminantshivcontinuity in treatmenttransgender women
spellingShingle Leonashia Leigh-Ann van der Merwe
Idah Moyo
Azwihangwisi H. Mavhandu-Mudzusi
Determinants of antiretroviral therapy adherence among transgender women in South Africa
South African Family Practice
art adherence
determinants
hiv
continuity in treatment
transgender women
title Determinants of antiretroviral therapy adherence among transgender women in South Africa
title_full Determinants of antiretroviral therapy adherence among transgender women in South Africa
title_fullStr Determinants of antiretroviral therapy adherence among transgender women in South Africa
title_full_unstemmed Determinants of antiretroviral therapy adherence among transgender women in South Africa
title_short Determinants of antiretroviral therapy adherence among transgender women in South Africa
title_sort determinants of antiretroviral therapy adherence among transgender women in south africa
topic art adherence
determinants
hiv
continuity in treatment
transgender women
url https://safpj.co.za/index.php/safpj/article/view/5869
work_keys_str_mv AT leonashialeighannvandermerwe determinantsofantiretroviraltherapyadherenceamongtransgenderwomeninsouthafrica
AT idahmoyo determinantsofantiretroviraltherapyadherenceamongtransgenderwomeninsouthafrica
AT azwihangwisihmavhandumudzusi determinantsofantiretroviraltherapyadherenceamongtransgenderwomeninsouthafrica