Antiviral Activity of Resveratrol against Human and Animal Viruses
Resveratrol is a potent polyphenolic compound that is being extensively studied in the amelioration of viral infections both in vitro and in vivo. Its antioxidant effect is mainly elicited through inhibition of important gene pathways like the NF-κβ pathway, while its antiviral effects are associate...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Advances in Virology |
| Online Access: | http://dx.doi.org/10.1155/2015/184241 |
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| _version_ | 1832555516309536768 |
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| author | Yusuf Abba Hasliza Hassim Hazilawati Hamzah Mohamed Mustapha Noordin |
| author_facet | Yusuf Abba Hasliza Hassim Hazilawati Hamzah Mohamed Mustapha Noordin |
| author_sort | Yusuf Abba |
| collection | DOAJ |
| description | Resveratrol is a potent polyphenolic compound that is being extensively studied in the amelioration of viral infections both in vitro and in vivo. Its antioxidant effect is mainly elicited through inhibition of important gene pathways like the NF-κβ pathway, while its antiviral effects are associated with inhibitions of viral replication, protein synthesis, gene expression, and nucleic acid synthesis. Although the beneficial roles of resveratrol in several viral diseases have been well documented, a few adverse effects have been reported as well. This review highlights the antiviral mechanisms of resveratrol in human and animal viral infections and how some of these effects are associated with the antioxidant properties of the compound. |
| format | Article |
| id | doaj-art-22d39e379e994bcf981e2a53c45dd81c |
| institution | Kabale University |
| issn | 1687-8639 1687-8647 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Virology |
| spelling | doaj-art-22d39e379e994bcf981e2a53c45dd81c2025-02-03T05:47:54ZengWileyAdvances in Virology1687-86391687-86472015-01-01201510.1155/2015/184241184241Antiviral Activity of Resveratrol against Human and Animal VirusesYusuf Abba0Hasliza Hassim1Hazilawati Hamzah2Mohamed Mustapha Noordin3Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, MalaysiaDepartment of Veterinary Preclinical Sciences, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, MalaysiaDepartment of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, MalaysiaDepartment of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, MalaysiaResveratrol is a potent polyphenolic compound that is being extensively studied in the amelioration of viral infections both in vitro and in vivo. Its antioxidant effect is mainly elicited through inhibition of important gene pathways like the NF-κβ pathway, while its antiviral effects are associated with inhibitions of viral replication, protein synthesis, gene expression, and nucleic acid synthesis. Although the beneficial roles of resveratrol in several viral diseases have been well documented, a few adverse effects have been reported as well. This review highlights the antiviral mechanisms of resveratrol in human and animal viral infections and how some of these effects are associated with the antioxidant properties of the compound.http://dx.doi.org/10.1155/2015/184241 |
| spellingShingle | Yusuf Abba Hasliza Hassim Hazilawati Hamzah Mohamed Mustapha Noordin Antiviral Activity of Resveratrol against Human and Animal Viruses Advances in Virology |
| title | Antiviral Activity of Resveratrol against Human and Animal Viruses |
| title_full | Antiviral Activity of Resveratrol against Human and Animal Viruses |
| title_fullStr | Antiviral Activity of Resveratrol against Human and Animal Viruses |
| title_full_unstemmed | Antiviral Activity of Resveratrol against Human and Animal Viruses |
| title_short | Antiviral Activity of Resveratrol against Human and Animal Viruses |
| title_sort | antiviral activity of resveratrol against human and animal viruses |
| url | http://dx.doi.org/10.1155/2015/184241 |
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