Design, Synthesis, and Biological Evaluations of a Novel Resveratrol-Type Analogue Against VEGF

Design, Synthesis, and Biological Evaluations of a Novel Resveratrol-Type Analogue Against VEGF

Vascular endothelial growth factor (VEGF), also known as VEGF-A, has been reported to mediate various diseases, including cancer and wet age-related macular degeneration (wAMD). Despite the fact that VEGF inhibitors are commercially available and appear to be effective in clinical applications, adve...

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Bibliographic Details
Main Authors: Shengying Lin, Maggie Suisui Guo, Roy Wai-Lun Tang, Yutong Ye, Jiahui Wu, Yuen Man Ho, Ran Duan, Ka Wing Leung, Tina Ting-Xia Dong, Karl Wah-Keung Tsim
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
Subjects:
VEGF inhibitor
SAR study
resveratrol-type analogs
angiogenesis
age-related macular degeneration
cancer
Online Access:https://www.mdpi.com/1420-3049/30/11/2345
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