Novel strategy for whole-genome sequencing of hepatitis A virus using NGS illumina technology and phylogenetic comparison with partial VP1/2A genomic region

Novel strategy for whole-genome sequencing of hepatitis A virus using NGS illumina technology and phylogenetic comparison with partial VP1/2A genomic region

Abstract Molecular epidemiology of hepatitis A virus (HAV) plays a critical role in identifying outbreak origin and conducting surveillance. Although it is mostly carried out using short partial VP1/2A genomic sequences, utilizing whole-genome sequences (WGS) provides more accurate and robust inform...

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Bibliographic Details
Main Authors: Paola Sicilia, Anabella Clara Fantilli, Facundo Cuba, Guadalupe Di Cola, María Gabriela Barbás, Tomás Poklepovich, Viviana Elizabeth Ré, Gonzalo Castro, María Belén Pisano
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Hepatitis A virus
HAV
NGS
Sequencing
Whole genome sequencing
Online Access:https://doi.org/10.1038/s41598-025-91116-7
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