Prevalence of autoimmune diseases in patients with type 1 diabetes: a scoping review

Prevalence of autoimmune diseases in patients with type 1 diabetes: a scoping review

ABSTRACT Objective To evaluate the prevalence of autoimmune diseases in patients with type 1 diabetes mellitus. Methods This scoping review was conducted following the Joanna Briggs Institute guidelines and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scop...

Full description

Saved in:
Bibliographic Details
Main Authors: Carlos Antonio Negrato, Rebecca Zerbinatti Pereira, Livia Domingos de Moraes Pimentel Porto, Ylana Walleska Santos Santana, Aline Kimmy Ikemoto Sato, Vitor Casoto de Melo, Miguel Luz Vilela Engel Vieira, Marilia de Brito Gomes
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2025-05-01
Series:Einstein (São Paulo)
Subjects:
Diabetes mellitus, type 1
Autoimmune diseases
Thyroiditis, autoimmune
Celiac disease
Addison disease
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082025000100405&lng=en&tlng=en
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:ABSTRACT Objective To evaluate the prevalence of autoimmune diseases in patients with type 1 diabetes mellitus. Methods This scoping review was conducted following the Joanna Briggs Institute guidelines and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) tool to ensure methodological rigor. We systematically searched PubMed, Embase, Scopus, Lilacs, and Web of Science databases to identify relevant literature published between 2018 and 2023. Results Twenty-four studies were included, mostly single-center studies from six continents, with varying study designs: 16 cross-sectional, seven retrospective, and one prospective cohort. The most prevalent autoimmune diseases found among patients with type 1 diabetes mellitus enrolled in these studies were autoimmune thyroiditis (5.5-41.2%), celiac disease (0.45-24.8%), rheumatoid arthritis (0.4-5.1%), and primary adrenal insufficiency (0.6-2.6%). Conclusion Autoimmune thyroiditis and celiac disease were the most prevalent autoimmune diseases in patients with type 1 diabetes mellitus. As the complexity of managing type 1 diabetes mellitus increases in the presence of multiple autoimmune comorbidities, further studies are required to elucidate the relationship between type 1 diabetes mellitus and different autoimmune pathologies. A deeper understanding of these associations will guide the development of public health policies, screening strategies, and educational initiatives tailored to the specific needs of this population.
ISSN:2317-6385

Similar Items